HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer[Biotin], His & Avi, Human
HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer[Biotin], His & Avi, Human

The purity of HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.

HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer[Biotin], His & Avi, Human

HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer[Biotin], His & Avi, Human

MAGE-A10 is a subtype of the Melanoma-associated antigen A (MAGE-A), a class of tumor antigens that are extensively expressed in various histological types of tumors and represents an attractive target for tumor immunotherapy. High-level expression of MAGE-A10 improved the anti-tumor immune cytotoxicity of MAGE-A10-specific CTLs in lung cancer cell lines and primary lung cancer cells.
Z06470
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Product Introduction
Species Human
Protein Construction
HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer [Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GLYDGMEHL peptide]
Accession # A0A140T913(HLA-A*02:01)&P61769(B2M)&GLYDGMEHL		 His Avi
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 50.44 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 53-63 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer[Biotin], His & Avi, Human
    • HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer[Biotin], His & Avi, Human

    The purity of HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.

  • HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer[Biotin], His & Avi, Human
    • HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer[Biotin], His & Avi, Human

    HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background MAGE-A10 is a subtype of the Melanoma-associated antigen A (MAGE-A), a class of tumor antigens that are extensively expressed in various histological types of tumors and represents an attractive target for tumor immunotherapy. High-level expression of MAGE-A10 improved the anti-tumor immune cytotoxicity of MAGE-A10-specific CTLs in lung cancer cell lines and primary lung cancer cells.
Synonyms MAGE-A10

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.