ITK, His & GST & Strep-II, Mouse

ITK, His & GST & Strep-II, Mouse

ITK (IL-2-inducible tyrosine kinase) belongs to the Tec family kinases and is mainly expressed in T cells. It is involved in TCR signalling events driving processes like T cell development as well as Th2, Th9 and Th17 responses thereby controlling the expression of pro-inflammatory cytokines.
Z06229
¥65,734.00

Ask us a question
Product Introduction
Species Mouse
Protein Construction
GST His ITK (Arg347-Leu625)
Accession # Q03526		 Strep-II
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System Baculovirus-Insect Cells
Theoretical Molecular Weight 61.42 kDa
Apparent Molecular Weight The protein has a predicted MW of 61.42 kDa same as Bis-Tris PAGE result.
Formulation Supplied as 0.22 μm filtered solution in 50mM Tris, 100mM NaCl, 10% Glycerol, 0.5mM GSH (pH 7.5).
Concentration Verified by one or more methods from A280/Bioactivity/BCA/Bradford.
Storage & Stability This product remains stable for 6 months at -80°C or below. Avoid repeated freeze-thaw cycles.

Background
Target Background ITK (IL-2-inducible tyrosine kinase) belongs to the Tec family kinases and is mainly expressed in T cells. It is involved in TCR signalling events driving processes like T cell development as well as Th2, Th9 and Th17 responses thereby controlling the expression of pro-inflammatory cytokines.
Synonyms Kinase EMT; Kinase TLK; Emt; Tlk; Tsk; Tcsk

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.