IGFBP-7 hFc Chimera, Mouse
IGFBP-7 HFc Chimera, Mouse

The purity of IGFBP-7 hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC.

IGFBP-7 HFc Chimera, Mouse

IGFBP-7 hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IGFBP-7 HFc Chimera, Mouse

IGFBP-7 hFc Chimera, Mouse on CM5 Chip via Protein A can bind Human CD93, His Tag with an affinity constant of 1.67 μM as determined in SPR assay (Biacore T200) (QC Test).

IGFBP-7 hFc Chimera, Mouse

IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
Z06175
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Product Introduction
Species Mouse
Protein Construction
IGFBP-7 (Ser26-Leu281)_x000D_
Accession # Q61581		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity IGFBP-7 hFc Chimera, Mouse captured on CM5 Chip via Protein A can bind Human CD93, His Tag in SPR assay (Biacore T200). Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 53.03 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • IGFBP-7 HFc Chimera, Mouse
    • IGFBP-7 HFc Chimera, Mouse

    The purity of IGFBP-7 hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC.

  • IGFBP-7 HFc Chimera, Mouse
    • IGFBP-7 HFc Chimera, Mouse

    IGFBP-7 hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • IGFBP-7 HFc Chimera, Mouse
    • IGFBP-7 HFc Chimera, Mouse

    IGFBP-7 hFc Chimera, Mouse on CM5 Chip via Protein A can bind Human CD93, His Tag with an affinity constant of 1.67 μM as determined in SPR assay (Biacore T200) (QC Test).


Background
Target Background IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
Synonyms IGFBP-7; IBP7; AGM; FSTL2; IGFBP-7v; IGFBPRP1; MAC25; PSF; RAMSVPS; TAF

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.