CDH17/Cadherin 17, His, Mouse
CDH17/Cadherin 17, His, Mouse

The purity of CDH17/Cadherin 17, His, Mouse is greater than 90% as determined by SEC-HPLC.

CDH17/Cadherin 17, His, Mouse

CDH17/Cadherin 17, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

CDH17/Cadherin 17, His, Mouse

Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Z06056
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Product Introduction
Species Mouse
Protein Construction
CDH17/Cadherin 17 (Phe26-Met786)_x000D_
Accession # Q9R100		 His
N-term C-term
Purity > 95% as determined by Bis­-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 85.4 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 90-115 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • CDH17/Cadherin 17, His, Mouse
    • CDH17/Cadherin 17, His, Mouse

    The purity of CDH17/Cadherin 17, His, Mouse is greater than 90% as determined by SEC-HPLC.

  • CDH17/Cadherin 17, His, Mouse
    • CDH17/Cadherin 17, His, Mouse

    CDH17/Cadherin 17, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Synonyms Cadherin-17; BILL-cadherin; LI-cadherin; P130; Cdh17; CDH16; HPT-1; cadherin-16; FLJ26931; MGC138218; MGC142024

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.