VCAM-1/CD106, His, Human
VCAM-1/CD106, His, Human

The purity of VCAM-1/CD106, His, Human is greater than 95% as determined by SEC-HPLC.

VCAM-1/CD106, His, Human

VCAM-1/CD106, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

VCAM-1/CD106, His, Human

Tumor necrosis factor alpha (TNFα) is a pro-inflammatory cytokine that triggers the expression of inflammatory molecules, including other cytokines and cell adhesion molecules. TNFα induces the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 (VCAM-1). VCAM-1 was originally identified as a cell adhesion molecule that helps regulate inflammation-associated vascular adhesion and the transendothelial migration of leukocytes, such as macrophages and T cells.
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Product Introduction
Species Human
Protein Construction
VCAM-1/CD106 (Phe25-Pro697)_x000D_
Accession # NP_001069		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 75.2 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 75-110 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • VCAM-1/CD106, His, Human
    • VCAM-1/CD106, His, Human

    The purity of VCAM-1/CD106, His, Human is greater than 95% as determined by SEC-HPLC.

  • VCAM-1/CD106, His, Human
    • VCAM-1/CD106, His, Human

    VCAM-1/CD106, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Tumor necrosis factor alpha (TNFα) is a pro-inflammatory cytokine that triggers the expression of inflammatory molecules, including other cytokines and cell adhesion molecules. TNFα induces the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 (VCAM-1). VCAM-1 was originally identified as a cell adhesion molecule that helps regulate inflammation-associated vascular adhesion and the transendothelial migration of leukocytes, such as macrophages and T cells.
Synonyms V-CAM 1; VCAM-1; INCAM-100; CD106; DKFZp779G2333; MGC99561

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.