NKp46/NCR1/CD335 mFc Chimera, Human
NKp46/NCR1/CD335 MFc Chimera, Human

Immobilized NKp46/NCR1/CD335 mFc Chimera, Human, mFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-Nkp46 Antibody, hFc Tag with the EC50 of 54.0ng/ml determined by ELISA.

NKp46/NCR1/CD335 MFc Chimera, Human

The purity of NKp46/NCR1/CD335 mFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

NKp46/NCR1/CD335 MFc Chimera, Human

NKp46/NCR1/CD335 mFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

NKp46/NCR1/CD335 mFc Chimera, Human

NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells.
Z05695
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Product Introduction
Species Human
Protein Construction
NKp46/NCR1/CD335 (Gln22-Asn255)_x000D_
Accession # O76036-1		 mFc (IgG1)
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 52.9 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 65-75 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • NKp46/NCR1/CD335 MFc Chimera, Human
    • NKp46/NCR1/CD335 MFc Chimera, Human

    Immobilized NKp46/NCR1/CD335 mFc Chimera, Human, mFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-Nkp46 Antibody, hFc Tag with the EC50 of 54.0ng/ml determined by ELISA.

  • NKp46/NCR1/CD335 MFc Chimera, Human
    • NKp46/NCR1/CD335 MFc Chimera, Human

    The purity of NKp46/NCR1/CD335 mFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

  • NKp46/NCR1/CD335 MFc Chimera, Human
    • NKp46/NCR1/CD335 MFc Chimera, Human

    NKp46/NCR1/CD335 mFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells.
Synonyms CD335; Ly94; NCR1; NKp46; MAR-1; NKP46FLJ99094

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.