NKG2C&CD94, His & Avi, Flag Human
NKG2C&CD94, His & Avi, Flag Human

The purity of NKG2C&CD94, His & Avi, Flag Human is greater than 95% as determined by SEC-HPLC.

NKG2C&CD94, His & Avi, Flag Human

NKG2C&CD94, His & Avi, Flag Human on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

NKG2C&CD94, His & Avi, Flag Human

NKG2C&CD94, His & Avi, Flag Human, His Tag immobilized on CM5 Chip can bind Human HLA-E*01:03 Complex Tetramer, His Tag with an affinity constant of 1.65 μM as determined in SPR assay (Biacore T200).

NKG2C&CD94, His & Avi, Flag Human

NKG2C&CD94 is a C-type lectin heterodimer on NK cells and CD8+ cytotoxic T-cells, it can recognize peptides derived from the intracellular proteins in the context of HLA-E. NKG2C&CD94 itself has no signal transduction function but is an activating receptor on the surface of NK cells that involved in driving the NK-cell expansion.
Z05688
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Product Introduction
Species Human
Protein Construction
Avi His NKG2C&CD94 (Glu98-Leu231(NKG2C)&Ser34-Ile179(CD94))_x000D_
Accession # P26717(NKG2C)&Q13241-1(CD94)
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 15.3kDa (NKG2C)&17.9kDa (CD94)
Apparent Molecular Weight Due to glycosylation, the protein migrates to 30-50 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • NKG2C&CD94, His & Avi, Flag Human
    • NKG2C&CD94, His & Avi, Flag Human

    The purity of NKG2C&CD94, His & Avi, Flag Human is greater than 95% as determined by SEC-HPLC.

  • NKG2C&CD94, His & Avi, Flag Human
    • NKG2C&CD94, His & Avi, Flag Human

    NKG2C&CD94, His & Avi, Flag Human on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

  • NKG2C&CD94, His & Avi, Flag Human
    • NKG2C&CD94, His & Avi, Flag Human

    NKG2C&CD94, His & Avi, Flag Human, His Tag immobilized on CM5 Chip can bind Human HLA-E*01:03 Complex Tetramer, His Tag with an affinity constant of 1.65 μM as determined in SPR assay (Biacore T200).


Background
Target Background NKG2C&CD94 is a C-type lectin heterodimer on NK cells and CD8+ cytotoxic T-cells, it can recognize peptides derived from the intracellular proteins in the context of HLA-E. NKG2C&CD94 itself has no signal transduction function but is an activating receptor on the surface of NK cells that involved in driving the NK-cell expansion.
Synonyms NKG2C&CD94; NKG2C; CD94

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.