IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human
IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human

Immobilized IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human, His Tag at 1 μg /ml (100 μl/well) on the plate. Dose response curve for Anti-IL-1 Rrp2 Antibody, hFc Tag with the EC50 of 4.8ng/ml determined by ELISA.

IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human

The purity of IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human is greater than 95% as determined by SEC-HPLC.

IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human

IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human

The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.
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Product Introduction
Species Human
Protein Construction
IL-1 Rrp2/IL-1 R6 (C154S, C262S) [Asp20-Tyr337 (C154S,C262S)]
Accession # Q9HB29-1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 37.2 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 56-67 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human
    • IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human

    Immobilized IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human, His Tag at 1 μg /ml (100 μl/well) on the plate. Dose response curve for Anti-IL-1 Rrp2 Antibody, hFc Tag with the EC50 of 4.8ng/ml determined by ELISA.

  • IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human
    • IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human

    The purity of IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human is greater than 95% as determined by SEC-HPLC.

  • IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human
    • IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human

    IL-1 Rrp2/IL-1 R6 (C154S, C262S), His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.
Synonyms IL-1 R6; IL-1 Rrp2; IL1RL2; IL1Rrp2; IL1RRP2; IL-36R

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.