HRG/HPRG, His, Human
HRG/HPRG, His, Human

The purity of HRG/HPRG, His, Human is greater than 95% as determined by SEC-HPLC.

HRG/HPRG, His, Human

HRG/HPRG, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

HRG/HPRG, His, Human

Histidine-rich glycoprotein (HRG) is a 75 kDa glycoprotein synthesized in the liver whose plasma concentration is 100-150 μg/ml. HRG has been shown to modulate sepsis-related biological reactions by binding to several substances and cells, including heparin, factor XII, fibrinogen, thrombospondin, plasminogen, C1q, IgG, heme, LPS, dead cells, bacteria, and fungi.
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Product Introduction
Species Human
Protein Construction
HRG/HPRG (Val19-Lys525)
Accession # NP_000403.1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 58.75 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • HRG/HPRG, His, Human
    • HRG/HPRG, His, Human

    The purity of HRG/HPRG, His, Human is greater than 95% as determined by SEC-HPLC.

  • HRG/HPRG, His, Human
    • HRG/HPRG, His, Human

    HRG/HPRG, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Histidine-rich glycoprotein (HRG) is a 75 kDa glycoprotein synthesized in the liver whose plasma concentration is 100-150 μg/ml. HRG has been shown to modulate sepsis-related biological reactions by binding to several substances and cells, including heparin, factor XII, fibrinogen, thrombospondin, plasminogen, C1q, IgG, heme, LPS, dead cells, bacteria, and fungi.
Synonyms HRG; HPRG; THPH11

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.