HGFA (pro form), His, Human
HGFA (pro Form), His, Human

The purity of HGFA (pro form), His, Human is greater than 95% as determined by SEC-HPLC.

HGFA (pro Form), His, Human

HGFA (pro form), His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

HGFA (pro form), His, Human

Hepatocyte growth factor activator (HGFA) is a serine protease initially identified as a potent activator of hepatocyte growth factor/scatter factor. Hepatocyte growth factor/scatter factor is known to be critically involved in tissue morphogenesis, regeneration, and tumor progression, via its receptor, MET.In vivo, HGFA also activates macrophage-stimulating protein, which has roles in macrophage recruitment and inflammatory processes, cellular survival and wound healing through its receptor, RON.
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Product Introduction
Species Human
Protein Construction
HGFA Protein (pro form) (Gln36-Ser655)
Accession # Q04756		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 67.2 kDa
Apparent Molecular Weight Due to glycosylation, the protein (pro form) migrates to 85-100 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • HGFA (pro Form), His, Human
    • HGFA (pro Form), His, Human

    The purity of HGFA (pro form), His, Human is greater than 95% as determined by SEC-HPLC.

  • HGFA (pro Form), His, Human
    • HGFA (pro Form), His, Human

    HGFA (pro form), His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Hepatocyte growth factor activator (HGFA) is a serine protease initially identified as a potent activator of hepatocyte growth factor/scatter factor. Hepatocyte growth factor/scatter factor is known to be critically involved in tissue morphogenesis, regeneration, and tumor progression, via its receptor, MET.In vivo, HGFA also activates macrophage-stimulating protein, which has roles in macrophage recruitment and inflammatory processes, cellular survival and wound healing through its receptor, RON.
Synonyms HGF activator; HGFA; Hgfac; MGC138395; MGC138397

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.