GIPR hFc Chimera, Human
GIPR HFc Chimera, Human

The purity of GIPR hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

GIPR HFc Chimera, Human

GIPR hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

GIPR hFc Chimera, Human

The gastric inhibitory polypeptide receptor (GIPR), a G protein-coupled receptor (GPCR) that regulates glucose metabolism and insulin secretion, is a target for the development of therapeutic agents to address type 2 diabetes and obesity.
Z05354
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Product Introduction
Species Human
Protein Construction
GIPR (Gly26-Gln138)
Accession # P48546-1		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 38.91 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • GIPR HFc Chimera, Human
    • GIPR HFc Chimera, Human

    The purity of GIPR hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

  • GIPR HFc Chimera, Human
    • GIPR HFc Chimera, Human

    GIPR hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background The gastric inhibitory polypeptide receptor (GIPR), a G protein-coupled receptor (GPCR) that regulates glucose metabolism and insulin secretion, is a target for the development of therapeutic agents to address type 2 diabetes and obesity.
Synonyms GIP-R; GIPR; PGQTL2

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.