GDF15, His, Human
GDF15, His, Human

Immobilized GDF15, His, Human, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 14.0 ng/ml determined by ELISA.

GDF15, His, Human

GDF15, His, Human on Bis-Tris PAGE under reduced (R) condition and Non reducing (N) condition. The purity is greater than 95%.

GDF15, His, Human

Human GFRAL, hFc Tag captured on CM5 Chip via Protein A can bind GDF15, His, Human, His Tag with an affinity constant of 0.014 nM as determined in SPR assay (Biacore T200).

GDF15, His, Human

Serial dilutions of Anti-GDF15 Antibody were added into Human GDF15, His Tag : BiotinylatedGDF15, His, Human, His Tag binding reactioins. The half maximal inhibitiory concentration(IC50) is 40.8ng/ml.

GDF15, His, Human

Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15.
Z05341
¥72,752.00

Ask us a question
Product Introduction
Species Human
Protein Construction
His GDF15 (Ala197-Ile308)
Accession # Q99988-1
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System E.coli
Theoretical Molecular Weight 13.5 kDa
Apparent Molecular Weight The protein migrates to 15-16 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in 50mM HAc (pH 2.9).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in 50mM HAc (pH 2.9).
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • GDF15, His, Human
    • GDF15, His, Human

    Immobilized GDF15, His, Human, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 14.0 ng/ml determined by ELISA.

  • GDF15, His, Human
    • GDF15, His, Human

    GDF15, His, Human on Bis-Tris PAGE under reduced (R) condition and Non reducing (N) condition. The purity is greater than 95%.

  • GDF15, His, Human
    • GDF15, His, Human

    Human GFRAL, hFc Tag captured on CM5 Chip via Protein A can bind GDF15, His, Human, His Tag with an affinity constant of 0.014 nM as determined in SPR assay (Biacore T200).

  • GDF15, His, Human
    • GDF15, His, Human

    Serial dilutions of Anti-GDF15 Antibody were added into Human GDF15, His Tag : BiotinylatedGDF15, His, Human, His Tag binding reactioins. The half maximal inhibitiory concentration(IC50) is 40.8ng/ml.


Background
Target Background Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15.
Synonyms GDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta; Placental TGF-β; PTGF-β; PTGFBPTGF-β

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.