IL-6, His, Cynomolgus
IL-6, His, Cynomolgus

Loaded IL-6, His, Cynomolgus, hFc Tag on ProA-Biosensor can bind Cynomolgus IL-6, His Tag with an affinity constant of 21.60 nM as determined in BLI assay (Gator® Prime).

IL-6, His, Cynomolgus

Immobilized IL-6, His, Cynomolgus, His Tag at 5 μg/ml(100 μl/well) on the plate. Dose response curve for Human IL-6 R alpha, hFc Tag with the EC50 of 6.6ng/ml determined by ELISA.

IL-6, His, Cynomolgus

The purity of IL-6, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

IL-6, His, Cynomolgus

IL-6, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IL-6, His, Cynomolgus

IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein.
Z04846
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Product Introduction
Species Cynomolgus
Protein Construction
IL-6 (Ala28-Met212)
Accession # P79341		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 22.06 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 25-30 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • IL-6, His, Cynomolgus
    • IL-6, His, Cynomolgus

    Loaded IL-6, His, Cynomolgus, hFc Tag on ProA-Biosensor can bind Cynomolgus IL-6, His Tag with an affinity constant of 21.60 nM as determined in BLI assay (Gator® Prime).

  • IL-6, His, Cynomolgus
    • IL-6, His, Cynomolgus

    Immobilized IL-6, His, Cynomolgus, His Tag at 5 μg/ml(100 μl/well) on the plate. Dose response curve for Human IL-6 R alpha, hFc Tag with the EC50 of 6.6ng/ml determined by ELISA.

  • IL-6, His, Cynomolgus
    • IL-6, His, Cynomolgus

    The purity of IL-6, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

  • IL-6, His, Cynomolgus
    • IL-6, His, Cynomolgus

    IL-6, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein.
Synonyms IFN-beta-2; IL6; IL-6; BSF-2; CDF; MGI-2A; Interleukin-6; HSF; IFNB2; HGF;IFN-β-2

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.