IL-22, His, Cynomolgus
IL-22, His, Cynomolgus

Immobilized IL-22, His, Cynomolgus, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human IL-22R alpha 1, hFc Tag with the EC50 of 99.5ng/ml determined by ELISA.

IL-22, His, Cynomolgus

The purity of IL-22, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

IL-22, His, Cynomolgus

IL-22, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IL-22, His, Cynomolgus

Cynomolgus IL-22R alpha 1, His Tag immobilized on CM5 Chip can bind CIL-22, His, Cynomolgus, His Tag with an affinity constant of 60.21 nM as determined in SPR assay (Biacore T200).

IL-22, His, Cynomolgus

The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production.
Z04835
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Product Introduction
Species Cynomolgus
Protein Construction
IL-22 (Ala34-Ile179)
Accession # G7PHZ7		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 17.69 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 32-42 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • IL-22, His, Cynomolgus
    • IL-22, His, Cynomolgus

    Immobilized IL-22, His, Cynomolgus, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human IL-22R alpha 1, hFc Tag with the EC50 of 99.5ng/ml determined by ELISA.

  • IL-22, His, Cynomolgus
    • IL-22, His, Cynomolgus

    The purity of IL-22, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

  • IL-22, His, Cynomolgus
    • IL-22, His, Cynomolgus

    IL-22, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • IL-22, His, Cynomolgus
    • IL-22, His, Cynomolgus

    Cynomolgus IL-22R alpha 1, His Tag immobilized on CM5 Chip can bind CIL-22, His, Cynomolgus, His Tag with an affinity constant of 60.21 nM as determined in SPR assay (Biacore T200).


Background
Target Background The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production.
Synonyms Interleukin-22; IL-22; Cytokine Zcyto18; IL-TIF; IL-D110; TIFa; TIFIL-23; ZCYTO18

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.