IFN gamma/IFNG, His, Cynomolgus
IFN Gamma/IFNG, His, Cynomolgus

Immobilized IFN gamma/IFNG, His, Cynomolgus, His Tag at 2 μg/ml(100 μl/well) on the plate. Dose response curve for Human IFNGR1, hFc Tag with the EC50 of 4.8ng/ml determined by ELISA.

IFN Gamma/IFNG, His, Cynomolgus

The purity of IFN gamma/IFNG, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

IFN Gamma/IFNG, His, Cynomolgus

IFN gamma/IFNG, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IFN gamma/IFNG, His, Cynomolgus

IFN-gamma and one of its receptor subunits, IFNGR1, are translocated to the nucleus, together with STAT1alpha as one macromolecular complex, via the classical importin-dependent pathway.Put IFN-gamma and its receptor subunit, IFNGR1, in direct contact with the promoter region of IFN-gamma-activated genes with associated increased activity, thus suggesting a transcriptional/cotranscriptional role for IFN-gamma/IFNGR1 as well as a possible role in determining the specificity of IFN-gamma action.
Z04813
¥72,752.00

Ask us a question
Product Introduction
Species Cynomolgus
Protein Construction
IFN gamma/IFNG (Gln24-Gln165)
Accession # P63309		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 17.72 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 25-35 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • IFN Gamma/IFNG, His, Cynomolgus
    • IFN Gamma/IFNG, His, Cynomolgus

    Immobilized IFN gamma/IFNG, His, Cynomolgus, His Tag at 2 μg/ml(100 μl/well) on the plate. Dose response curve for Human IFNGR1, hFc Tag with the EC50 of 4.8ng/ml determined by ELISA.

  • IFN Gamma/IFNG, His, Cynomolgus
    • IFN Gamma/IFNG, His, Cynomolgus

    The purity of IFN gamma/IFNG, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

  • IFN Gamma/IFNG, His, Cynomolgus
    • IFN Gamma/IFNG, His, Cynomolgus

    IFN gamma/IFNG, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background IFN-gamma and one of its receptor subunits, IFNGR1, are translocated to the nucleus, together with STAT1alpha as one macromolecular complex, via the classical importin-dependent pathway.Put IFN-gamma and its receptor subunit, IFNGR1, in direct contact with the promoter region of IFN-gamma-activated genes with associated increased activity, thus suggesting a transcriptional/cotranscriptional role for IFN-gamma/IFNGR1 as well as a possible role in determining the specificity of IFN-gamma action.
Synonyms IFN-gamma-R1; CDw119; CD119; IFNGR1; IFNGR; AVP; FLJ45734; IFN-gamma R1; IFN-gR1; type 2; IFNγ; IFN γ

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.