GAS6, His, Cynomolgus
GAS6, His, Cynomolgus

Immobilized GAS6, His, Cynomolgus, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-Gas6 Antibody, hFc Tag with the EC50 of 10.0ng/ml determined by ELISA.

GAS6, His, Cynomolgus

The purity of GAS6, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

GAS6, His, Cynomolgus

GAS6, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

GAS6, His, Cynomolgus

Cynomolgus Axl, His Tag immobilized on CM5 Chip can bind GAS6, His, Cynomolgus, His Tag with an affinity constant of 1.70 nM as determined in SPR assay (Biacore T200).

GAS6, His, Cynomolgus

Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM).
Z04798
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Product Introduction
Species Cynomolgus
Protein Construction
GAS6 (Ala31-Ala637)
Accession # A0A2K5VGX7		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 68.55 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 69-74 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • GAS6, His, Cynomolgus
    • GAS6, His, Cynomolgus

    Immobilized GAS6, His, Cynomolgus, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-Gas6 Antibody, hFc Tag with the EC50 of 10.0ng/ml determined by ELISA.

  • GAS6, His, Cynomolgus
    • GAS6, His, Cynomolgus

    The purity of GAS6, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

  • GAS6, His, Cynomolgus
    • GAS6, His, Cynomolgus

    GAS6, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • GAS6, His, Cynomolgus
    • GAS6, His, Cynomolgus

    Cynomolgus Axl, His Tag immobilized on CM5 Chip can bind GAS6, His, Cynomolgus, His Tag with an affinity constant of 1.70 nM as determined in SPR assay (Biacore T200).


Background
Target Background Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM).
Synonyms GAS-6; AXLLG; GAS6; DKFZp666G247; FLJ34709

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.