Immobilized IL-23 alpha&IL-12 beta[Biotin], His & Avi, Human, His Tag at 2 μg/ml (100 μl/Well) on streptavidin(5 μg/ml) precoated plate. Dose response curve for Human IL-23R, hFc Tag with the EC50 of 19.2 ng/ml determined by ELISA.
Immobilized IL-23 alpha&IL-12 beta[Biotin], His & Avi, Human, His Tag at 0.5 μg/ml (100 μl/Well) on streptavidin(5 μg/ml) precoated plate. Dose response curve for Anti-IL-23 Antibody, hFc Tag with the EC50 of 2.2 ng/ml determined by ELISA.
The purity of IL-23 alpha&IL-12 beta[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.
IL-23 alpha&IL-12 beta[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
IL-23 alpha&IL-12 beta[Biotin], His & Avi, Human
The interleukin (IL)-12 family of cytokines, including IL12 and IL 23, play an important role in driving aberrant Th1 and Th17 immune responses in patients with Crohn's disease (CD). Targeting this pathway has opened new avenues for therapeutic intervention. The balance of proinflammatory cytokines interleukin (IL)-12 and IL-23 plays a key role in shaping the development of antitumor or protumor immunity.
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