Her3/ErbB3 hFc Chimera, Human
Her3/ErbB3 HFc Chimera, Human

Her3/ErbB3 hFc Chimera, Human on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

Her3/ErbB3 HFc Chimera, Human

The purity of Her3/ErbB3 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

Her3/ErbB3 HFc Chimera, Human

Immobilized Her3/ErbB3 hFc Chimera, Human at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human NRG1 Beta 1, hFc Tag with the EC50 of 0.51 μg/ml determined by ELISA.

Her3/ErbB3 HFc Chimera, Human

Immobilized Her3/ErbB3 hFc Chimera, Human, hFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-HER3 Antibody, hFc Tag with the EC50 of 10.7 ng/ml determined by ELISA.

Her3/ErbB3 hFc Chimera, Human

Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).
Z03906
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Product Introduction
Species Human
Protein Construction
Her3/ErbB3 (Ser20-Thr643)
Accession # P21860		 hFc
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 95.4 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 110-120 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 μg/ml.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • Her3/ErbB3 HFc Chimera, Human
    • Her3/ErbB3 HFc Chimera, Human

    Her3/ErbB3 hFc Chimera, Human on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

  • Her3/ErbB3 HFc Chimera, Human
    • Her3/ErbB3 HFc Chimera, Human

    The purity of Her3/ErbB3 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

  • Her3/ErbB3 HFc Chimera, Human
    • Her3/ErbB3 HFc Chimera, Human

    Immobilized Her3/ErbB3 hFc Chimera, Human at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human NRG1 Beta 1, hFc Tag with the EC50 of 0.51 μg/ml determined by ELISA.

  • Her3/ErbB3 HFc Chimera, Human
    • Her3/ErbB3 HFc Chimera, Human

    Immobilized Her3/ErbB3 hFc Chimera, Human, hFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-HER3 Antibody, hFc Tag with the EC50 of 10.7 ng/ml determined by ELISA.


Background
Target Background Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).
Synonyms ErbB3; ErbB-3; HER3; HER3c-erbB-3; LCCS2; MDA-BF-1; MGC88033; p180-ErbB3; p45-sErbB3; p85-sErbB3; ERBB3

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.