PD-1 Antibody (2E5), mAb, Mouse
PD-1 (2E5), MAb, Mouse

Immunohistochemistry analysis of human Lymph node slide (Paraffin embedded) using PD-1 Antibody, mAb, Mouse (GenScript, Cat. V02201)

PD-1 (2E5), mAb, Mouse

Programmed Cell Death Protein 1 (PD-1), is cell surface receptor expressing on T cells and pro-B cells. The binding of PD-1 to its two ligands, PD-L1 and PD-L2, could result in down-regulation of the immune system by inhibiting the T-cell activation process. Thus, PD-1 is an important immune checkpoint and a popular target for therapeutic antibodies against many cancers.
V02201
¥53,831.00

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Overview
Specificity Human PD-1
Clone ID 2E5
Isotype IgG1
Subclass IgG1
Host Species Mouse
Antigen Species Human

Properties
Conjugation Unconjugated
Production Cultured in vitro under conditions free from animal-derived components
Purification Protein A/G affinity column
Concentration ≥ 2mg/ml
Formulation 50 mM Na-citrate, 150 mM NaCl, pH 7.0, containing 0.03% ProClin 300.
Storage For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
Note GenScript can customize this product per customer's request including product size, buffer components, etc.

Applications
IHC

Examples
  • PD-1 (2E5), MAb, Mouse
    • PD-1 (2E5), MAb, Mouse

    Immunohistochemistry analysis of human Lymph node slide (Paraffin embedded) using PD-1 Antibody, mAb, Mouse (GenScript, Cat. V02201)


Background
Target Background Programmed Cell Death Protein 1 (PD-1), is cell surface receptor expressing on T cells and pro-B cells. The binding of PD-1 to its two ligands, PD-L1 and PD-L2, could result in down-regulation of the immune system by inhibiting the T-cell activation process. Thus, PD-1 is an important immune checkpoint and a popular target for therapeutic antibodies against many cancers.

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.