p-ErbB2 (Y1139) Antibody, mAb, Rabbit
P-ErbB2 (Y1139) Antibody, MAb, Rabbit

Western blot analysis of Phospho-ErbB2 (Y1139) expression in (1) A431 cell lysate; (2) A431 treated with EGF cell lysate.

p-ErbB2 (Y1139) Antibody, mAb, Rabbit

Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone.
A05389
¥37,309.00

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Overview
Specificity This product is specific to p-ErbB2 (Y1139)
Host Species Rabbit
Immunogen A synthesized peptide derived from human ErbB2 around the phosphorylation site of Y1139
Species Reactivity Human
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunoprecipitation (IP) 1:20-1:50

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • P-ErbB2 (Y1139) Antibody, MAb, Rabbit
    • P-ErbB2 (Y1139) Antibody, MAb, Rabbit

    Western blot analysis of Phospho-ErbB2 (Y1139) expression in (1) A431 cell lysate; (2) A431 treated with EGF cell lysate.


Background
Target Background Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone.
Synonyms CD340; CerbB2; ERBB2; HER2; Herstatin; MLN19; NEU; NGL; p185erbB2; TKR1;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.