SKP2 Antibody, mAb, Rabbit
SKP2 Antibody, MAb, Rabbit

Western blot analysis of SKP2 expression in HeLa cell lysate.

SKP2 Antibody, mAb, Rabbit

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription.
A05181
¥37,309.00

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Overview
Specificity This product is specific to SKP2
Host Species Rabbit
Immunogen A synthesized peptide derived from human SKP2
Species Reactivity Human
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • SKP2 Antibody, MAb, Rabbit
    • SKP2 Antibody, MAb, Rabbit

    Western blot analysis of SKP2 expression in HeLa cell lysate.


Background
Target Background Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription.
Synonyms FBL1; FBXL1; FLB1; p45; p45skp2; Skp2;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.