p-p90 S6K alpha 1 (T573) Antibody, mAb, Rabbit

p-p90 S6K alpha 1 (T573) Antibody, mAb, Rabbit

Forms a complex with either MAPK1/ERK2 or MAPK3/ERK1 in quiescent cells. Transiently dissociates following mitogenic stimulation. Interacts with ETV1/ER81 and FGFR1.(Microbial infection) Interacts with Kaposi's sarcoma-associated herpesvirus/HHV-8 protein ORF45; this interaction allows RPS6KA1 activation.
A05170
¥37,309.00

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Overview
Specificity This product is specific to p-p90 S6K alpha 1 (T573)
Host Species Rabbit
Immunogen A synthesized peptide derived from human p90 S6K alpha 1 around the phosphorylation site of T573
Species Reactivity Human
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Background
Target Background Forms a complex with either MAPK1/ERK2 or MAPK3/ERK1 in quiescent cells. Transiently dissociates following mitogenic stimulation. Interacts with ETV1/ER81 and FGFR1.(Microbial infection) Interacts with Kaposi's sarcoma-associated herpesvirus/HHV-8 protein ORF45; this interaction allows RPS6KA1 activation.
Synonyms HU1; MAPKAPK1A; p90rsk; p90RSK1; p90S6K; pp90RSK1; Ribosomal protein S6 kinase alpha 1; Ribosomal S6 kinase 1; RPS6K1; rps6ka; Rps6ka1; RSK; RSK1; S6K alpha 1;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.