NRG3 Antibody, mAb, Rabbit
NRG3 Antibody, MAb, Rabbit

Western blot analysis of NRG3 expression in (1) SH-SY5Y cell lysate; (2) C6 cell lysate.

NRG3 Antibody, mAb, Rabbit

Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes.
A05166
¥37,309.00

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Overview
Specificity This product is specific to NRG3
Host Species Rabbit
Immunogen A synthesized peptide derived from human NRG3
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Flow Cytometry 1:20-1:100

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • NRG3 Antibody, MAb, Rabbit
    • NRG3 Antibody, MAb, Rabbit

    Western blot analysis of NRG3 expression in (1) SH-SY5Y cell lysate; (2) C6 cell lysate.


Background
Target Background Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes.
Synonyms HRG3; Neuregulin 3; Nrg3; Pro neuregulin 3;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.