p-Chk1 (S280) Antibody, mAb, Rabbit
P-Chk1 (S280) Antibody, MAb, Rabbit

Western blot analysis of Phospho-Chk1 (S280) expression in 293T treated with Calyculin A cell lysate.

p-Chk1 (S280) Antibody, mAb, Rabbit

Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA.
A05121
¥37,309.00

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Overview
Specificity This product is specific to p-Chk1 (S280)
Host Species Rabbit
Immunogen A synthesized peptide derived from human Chk1 around the phosphorylation site of S280
Species Reactivity Human
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • P-Chk1 (S280) Antibody, MAb, Rabbit
    • P-Chk1 (S280) Antibody, MAb, Rabbit

    Western blot analysis of Phospho-Chk1 (S280) expression in 293T treated with Calyculin A cell lysate.


Background
Target Background Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA.
Synonyms Checkpoint kinase 1; Chek1; Chk1; rad27;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.