PRKRA Antibody, mAb, Rabbit
PRKRA Antibody, MAb, Rabbit

Western blot analysis of PRKRA expression in HepG2 cell lysate.

PRKRA Antibody, mAb, Rabbit

Activates EIF2AK2/PKR in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing.
A04575
¥37,309.00

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Overview
Specificity This product is specific to PRKRA
Host Species Rabbit
Immunogen A synthesized peptide derived from human PRKRA
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • PRKRA Antibody, MAb, Rabbit
    • PRKRA Antibody, MAb, Rabbit

    Western blot analysis of PRKRA expression in HepG2 cell lysate.


Background
Target Background Activates EIF2AK2/PKR in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing.
Synonyms RAX; PACT; DYT16; HSD14;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.