TREX1 Antibody, mAb, Rabbit
TREX1 Antibody, MAb, Rabbit

Western blot analysis of TREX1 expression in Daudi cell lysate.

TREX1 Antibody, mAb, Rabbit

Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini.Prevents cell-intrinsic initiation of autoimmunity.Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements.
A04429
¥37,309.00

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Overview
Specificity This product is specific to TREX1
Host Species Rabbit
Immunogen A synthesized peptide derived from human TREX1
Species Reactivity Human
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Immunohistochemistry Frozen (IHF) 1:50-1:200

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • TREX1 Antibody, MAb, Rabbit
    • TREX1 Antibody, MAb, Rabbit

    Western blot analysis of TREX1 expression in Daudi cell lysate.


Background
Target Background Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini.Prevents cell-intrinsic initiation of autoimmunity.Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements.
Synonyms AGS1; AGS5; CRV; DNase III; DRN3; HERNS; TREX1;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.