KIF2C Antibody, mAb, Rabbit

KIF2C Antibody, mAb, Rabbit

In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells.Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis.Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment.
A04423
¥37,309.00

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Overview
Specificity This product is specific to KIF2C
Host Species Rabbit
Immunogen A synthesized peptide derived from human KIF2C
Species Reactivity Human
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Flow Cytometry 1:20-1:100

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Background
Target Background In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells.Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis.Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment.
Synonyms MCAK; KNSL6;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.