Western blot analysis of DISC1 expression in (1) HeLa cell lysate; (2) RAW264.7 cell lysate; (3) PC-12 cell lysate.
DISC1 Antibody, mAb, Rabbit
Involved in the regulation of multiple aspects of embryonic and adult neurogenesis.Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus.Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance.
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