Meckelin Antibody, mAb, Rabbit
Meckelin Antibody, MAb, Rabbit

Western blot analysis of Meckelin expression in (1) MCF7 cell lysate; (2) RAW 264.7 cell lysate; (3) C6 cell lysate.

Meckelin Antibody, mAb, Rabbit

Required for ciliary structure and function. Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition.Involved in centrosome migration to the apical cell surface during early ciliogenesis. Involved in the regulation of cilia length and appropriate number through the control of centrosome duplication. Is a key regulator of stereociliary bundle orientation.
A04162
¥37,309.00

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Overview
Specificity This product is specific to Meckelin
Host Species Rabbit
Immunogen A synthesized peptide derived from human Meckelin
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Immunohistochemistry Frozen (IHF) 1:50-1:200
Flow Cytometry 1:20-1:100

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • Meckelin Antibody, MAb, Rabbit
    • Meckelin Antibody, MAb, Rabbit

    Western blot analysis of Meckelin expression in (1) MCF7 cell lysate; (2) RAW 264.7 cell lysate; (3) C6 cell lysate.


Background
Target Background Required for ciliary structure and function. Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition.Involved in centrosome migration to the apical cell surface during early ciliogenesis. Involved in the regulation of cilia length and appropriate number through the control of centrosome duplication. Is a key regulator of stereociliary bundle orientation.
Synonyms JBTS6; MKS3; NPHP11; TMEM67; TNEM67;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.