xCT Antibody, mAb, Rabbit
XCT Antibody, MAb, Rabbit

Western blot analysis of xCT expression in (1) HepG2 cell lysate; (2) Mouse brain lysate.

xCT Antibody, mAb, Rabbit

Heterodimer with SLC3A2, that functions as an antiporter by mediating the exchange of extracellular anionic L-cystine and intracellular L-glutamate across the cellular plasma membrane.Provides L-cystine for the maintenance of the redox balance between extracellular L-cystine and L-cysteine and for the maintenance of the intracellular levels of glutathione that is essential for cells protection from oxidative stress.
A03854
¥37,309.00

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Overview
Specificity This product is specific to xCT
Host Species Rabbit
Immunogen A synthesized peptide derived from human xCT
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Immunoprecipitation (IP) 1:20-1:50

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • XCT Antibody, MAb, Rabbit
    • XCT Antibody, MAb, Rabbit

    Western blot analysis of xCT expression in (1) HepG2 cell lysate; (2) Mouse brain lysate.


Background
Target Background Heterodimer with SLC3A2, that functions as an antiporter by mediating the exchange of extracellular anionic L-cystine and intracellular L-glutamate across the cellular plasma membrane.Provides L-cystine for the maintenance of the redox balance between extracellular L-cystine and L-cysteine and for the maintenance of the intracellular levels of glutathione that is essential for cells protection from oxidative stress.
Synonyms CCBR1; Cysteine/glutamate transporter; SLC7A11; solute carrier family 7; xCT;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.