ABCC1 Antibody, mAb, Rabbit
ABCC1 Antibody, MAb, Rabbit

Western blot analysis of MRP1 expression in A431 cell lysate.

ABCC1 Antibody, mAb, Rabbit

Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
A03688
¥37,309.00

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Overview
Specificity This product is specific to ABCC1
Host Species Rabbit
Immunogen A synthesized peptide derived from human ABCC1
Species Reactivity Human
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Flow Cytometry 1:20-1:100

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • ABCC1 Antibody, MAb, Rabbit
    • ABCC1 Antibody, MAb, Rabbit

    Western blot analysis of MRP1 expression in A431 cell lysate.


Background
Target Background Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
Synonyms ABC29; Abcc1; GSX; Leukotriene C(4) transporter; LTC4 transporter; MRP1;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.