PD L1 Antibody, mAb, Rabbit
PD L1 Antibody, MAb, Rabbit

Western blot analysis of PD-L1 (CD274) expression in Ramos cell lysate.

PD L1 Antibody, mAb, Rabbit

Plays a critical role in induction and maintenance of immune tolerance to self.As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response.Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10).
A03359
¥37,309.00

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Overview
Specificity This product is specific to PD L1
Host Species Rabbit
Immunogen A synthesized peptide derived from human PD L1
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • PD L1 Antibody, MAb, Rabbit
    • PD L1 Antibody, MAb, Rabbit

    Western blot analysis of PD-L1 (CD274) expression in Ramos cell lysate.


Background
Target Background Plays a critical role in induction and maintenance of immune tolerance to self.As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response.Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10).
Synonyms B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; CD274;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.