HIF 1 alpha Antibody, mAb, Rabbit
HIF 1 Alpha Antibody, MAb, Rabbit

Western blot analysis of HIF-1-alpha expression in HeLa treated with CoCl2 cell lysate.

HIF 1 alpha Antibody, mAb, Rabbit

Functions as a master transcriptional regulator of the adaptive response to hypoxia.Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia.
A03207
¥37,309.00

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Overview
Specificity This product is specific to HIF 1 alpha
Host Species Rabbit
Immunogen A synthesized peptide derived from human HIF 1 alpha
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • HIF 1 Alpha Antibody, MAb, Rabbit
    • HIF 1 Alpha Antibody, MAb, Rabbit

    Western blot analysis of HIF-1-alpha expression in HeLa treated with CoCl2 cell lysate.


Background
Target Background Functions as a master transcriptional regulator of the adaptive response to hypoxia.Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia.
Synonyms HIF1; MOP1; PASD8; bHLHe78; HIF-1alpha; HIF1-ALPHA; HIF1A

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.