Caspase 9 Antibody, mAb, Rabbit
Caspase 9 Antibody, MAb, Rabbit

Western blot analysis of Caspase 9 Antibody, mAb, Rabbit expression in HeLa cell lysate treated with staurosporine.

Caspase 9 Antibody, mAb, Rabbit

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
A03065
¥37,309.00

Ask us a question
Overview
Specificity This product is specific to Caspase 9
Host Species Rabbit
Immunogen A synthesized peptide derived from human Caspase 9
Species Reactivity Human; Mouse
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunoprecipitation (IP) 1:20-1:50

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • Caspase 9 Antibody, MAb, Rabbit
    • Caspase 9 Antibody, MAb, Rabbit

    Western blot analysis of Caspase 9 Antibody, mAb, Rabbit expression in HeLa cell lysate treated with staurosporine.


Background
Target Background Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
Synonyms MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; CASP9; Caspase-9; Caspase 9 Dominant Negative;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.