DARPP 32 Antibody, mAb, Rabbit
DARPP 32 Antibody, MAb, Rabbit

Western blot analysis of DARPP-32 expression in Rat brain lysate.

DARPP 32 Antibody, mAb, Rabbit

This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.
A02768
¥37,309.00

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Overview
Specificity This product is specific to DARPP 32
Host Species Rabbit
Immunogen A synthesized peptide derived from human DARPP 32
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Immunohistochemistry Frozen (IHF) 1:50-1:200
Immunoprecipitation (IP) 1:20-1:50

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • DARPP 32 Antibody, MAb, Rabbit
    • DARPP 32 Antibody, MAb, Rabbit

    Western blot analysis of DARPP-32 expression in Rat brain lysate.


Background
Target Background This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms DARPP32; PPP1R1B; PPR1B; Protein phosphatase 1 regulatory subunit 1B;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.