SHP1 Antibody, mAb, Rabbit
SHP1 Antibody, MAb, Rabbit

Western blot analysis of SHP1 expression in Jurkat cell lysate.

SHP1 Antibody, mAb, Rabbit

Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
A02755
¥37,309.00

Ask us a question
Overview
Specificity This product is specific to SHP1
Host Species Rabbit
Immunogen A synthesized peptide derived from human SHP1
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • SHP1 Antibody, MAb, Rabbit
    • SHP1 Antibody, MAb, Rabbit

    Western blot analysis of SHP1 expression in Jurkat cell lysate.


Background
Target Background Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
Synonyms 70Z-SHP; EC 3.1.3.48; HCP; HCPH; PTN6; PTP-1C; PTP1C; PTPN6; SH-PTP1; SHP1;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.