Glutamate carboxypeptidase 2 Antibody, mAb, Rabbit
Glutamate Carboxypeptidase 2 Antibody, MAb, Rabbit

Western blot analysis of PSMA expression in LnCaP cell lysate.

Glutamate carboxypeptidase 2 Antibody, mAb, Rabbit

Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.
A02592
¥37,309.00

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Overview
Specificity This product is specific to Glutamate carboxypeptidase 2
Host Species Rabbit
Immunogen A synthesized peptide derived from human Glutamate carboxypeptidase 2
Species Reactivity Human
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Immunohistochemistry Frozen (IHF) 1:50-1:200
Immunoprecipitation (IP) 1:20-1:50

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • Glutamate Carboxypeptidase 2 Antibody, MAb, Rabbit
    • Glutamate Carboxypeptidase 2 Antibody, MAb, Rabbit

    Western blot analysis of PSMA expression in LnCaP cell lysate.


Background
Target Background Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.
Synonyms FGCP;FOLH 1;GCP 2;GCPII;mGCP;NAALADase I;PSM;PSMA

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.