p-Acetyl CoA carboxylase 1 (S80) Antibody, mAb, Rabbit
P-Acetyl CoA Carboxylase 1 (S80) Antibody, MAb, Rabbit

Western blot analysis of Phospho-ACC(S79) expression in (1) A431 cell lysate; (2) A431 cell treated with lambda phosphatase lysate.

p-Acetyl CoA carboxylase 1 (S80) Antibody, mAb, Rabbit

Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis.This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA.
A02502
¥37,309.00

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Overview
Specificity This product is specific to p-Acetyl CoA carboxylase 1 (S80)
Host Species Rabbit
Immunogen A synthesized peptide derived from human Acetyl CoA carboxylase 1 around the phosphorylation site of S79
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • P-Acetyl CoA Carboxylase 1 (S80) Antibody, MAb, Rabbit
    • P-Acetyl CoA Carboxylase 1 (S80) Antibody, MAb, Rabbit

    Western blot analysis of Phospho-ACC(S79) expression in (1) A431 cell lysate; (2) A431 cell treated with lambda phosphatase lysate.


Background
Target Background Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis.This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA.
Synonyms ACAC; ACACA; ACACB; ACC alpha; ACC; ACC beta; ACC1; ACC2; ACCA; ACCB; Acetyl CoA carboxylase 1; Acetyl CoA carboxylase 2;COA1; COA2;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.