SLC38A2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC38A2
Entrez Gene ID	54407
Full Name	solute carrier family 38 member 2
Synonyms	ATA2,PRO1068,SAT2,SNAT2
General protein information	Preferred Names solute carrier family 38 member 2 Names sodium-coupled neutral amino acid transporter 2 amino acid transporter 2 amino acid transporter A2 protein 40-9-1 system A amino acid transporter 2 system A transporter 1 system N amino acid transporter 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q13.11
Disorder MIM:	605180

mRNA and Protein(s)

mRNA	Protein	Name
NM_001307936.1	NP_001294865.1	sodium-coupled neutral amino acid transporter 2 isoform 2 precursor
NM_018976.4	NP_061849.2	sodium-coupled neutral amino acid transporter 2 isoform 1
NM_001307936.2	NP_001294865.1	sodium-coupled neutral amino acid transporter 2 isoform 2 precursor
NM_018976.5	NP_061849.2	sodium-coupled neutral amino acid transporter 2 isoform 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Slc38a2	NP_851604.1
Danio rerio (zebrafish)	slc38a2	NP_001038569.1
Homo sapiens (human)	SLC38A2	NP_061849.2
Pan troglodytes (chimpanzee)	SLC38A2	XP_001164321.1
	SLC38A2	XP_002798588.1
Canis lupus familiaris (dog)	SLC38A2	XP_005637001.1
Bos taurus (cattle)	SLC38A2	NP_001075893.1
Mus musculus (house mouse)	Slc38a2	NP_780330.2
Xenopus tropicalis (tropical clawed frog)	slc38a2	NP_001011056.1
Gallus gallus (chicken)	SLC38A2	NP_001025912.1

Gene Ontology
Bibliography

Related articles in PubMed

Influence of nutrient ingestion on amino acid transporters and protein synthesis in human skeletal muscle after sprint exercise.
Rundqvist HC, Esbj?rnsson M, Rooyackers O, ?sterlund T, Moberg M, Apro W, Blomstrand E, Jansson E
Journal of applied physiology (Bethesda, Md. : 1985)123(6)1501-1515(2017 Dec)

Deletion of Amino Acid Transporter ASCT2 (SLC1A5) Reveals an Essential Role for Transporters SNAT1 (SLC38A1) and SNAT2 (SLC38A2) to Sustain Glutaminolysis in Cancer Cells.
Br?er A, Rahimi F, Br?er S
The Journal of biological chemistry291(25)13194-205(2016 Jun)

Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2.
Rosario FJ, Dimasuay KG, Kanai Y, Powell TL, Jansson T
Clinical science (London, England : 1979)130(7)499-512(2016 Apr)

Identification of a Disulfide Bridge in Sodium-Coupled Neutral Amino Acid Transporter 2(SNAT2) by Chemical Modification.
Chen C, Wang J, Cai R, Yuan Y, Guo Z, Grewer C, Zhang Z
PloS one11(6)e0158319(2016)

Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR.
Chen YY, Rosario FJ, Shehab MA, Powell TL, Gupta MB, Jansson T
Clinical science (London, England : 1979)129(12)1131-41(2015 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In the absence of SLC1A5 there is a crucial role of SNAT1 in supplying glutamine for glutaminolysis with SNAT2 acting as a "backup" for glutamine transport.
Title: Deletion of Amino Acid Transporter ASCT2 (SLC1A5) Reveals an Essential Role for Transporters SNAT1 (SLC38A1) and SNAT2 (SLC38A2) to Sustain Glutaminolysis in Cancer Cells.

Propose regulation of placental SNAT2/LAT1 ubiquitination by mTORC1 and Nedd4-2.
Title: Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2.

there is a disulfide bond between Cys245 and Cys279 in SNAT2 which has no effect on cell surface trafficking, as well as transporter function
Title: Identification of a Disulfide Bridge in Sodium-Coupled Neutral Amino Acid Transporter 2(SNAT2) by Chemical Modification.

Decreased placental mTOR activity causes down-regulation of placental system A activity by shifting SNAT-2 trafficking towards proteasomal degradation, thereby contributing to decreased fetal amino acid availability and restricted fetal growth in IUGR.
Title: Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR.

GADD34 promotes cell survival and adaptation to increased extracellular osmolarity by increasing the uptake of small neutral amino acids via the amino acid transporter SNAT2.
Title: Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity.

The following SLC38A2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC38A2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09064	NM_018976.5 Latest version!	Homo sapiens solute carrier family 38 member 2 (SLC38A2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu46643	NM_001307936.2 Latest version!	Homo sapiens solute carrier family 38 member 2 (SLC38A2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu46643	NM_001307936.1	Homo sapiens solute carrier family 38 member 2 (SLC38A2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu09064	NM_018976.4	Homo sapiens solute carrier family 38 member 2 (SLC38A2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC38A2 ( NM_018976.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_061849.2 Homo sapiens solute carrier family 38 member 2 (SLC38A2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09064
Clone ID Related Accession (Same CDS sequence)	NM_018976.4 , NM_018976.5
Accession Version	NM_018976.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1521bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	sodium-coupled neutral amino acid transporter 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA725217.1, BC040342.1 and AC025031.30. On Jan 6, 2009 this sequence version replaced NM_018976.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC040342.1, SRR1660809.173821.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGAAGG CCGAAATGGG ACGATTCAGT ATTTCCCCGG ATGAAGACAG CAGCAGCTAC 
AGTTCCAACA GCGACTTCAA CTACTCCTAC CCCACCAAGC AAGCTGCTCT GAAAAGCCAT 
TATGCAGATG TAGATCCTGA AAACCAGAAC TTTTTACTTG AATCGAATTT GGGGAAGAAG 
AAGTATGAAA CAGAATTTCA TCCAGGTACT ACTTCCTTTG GAATGTCAGT ATTTAATCTG 
AGCAATGCGA TTGTGGGCAG TGGAATCCTT GGGCTTTCTT ATGCCATGGC TAATACTGGA 
ATTGCTCTTT TTATAATTCT CTTGACATTT GTGTCAATAT TTTCCCTGTA TTCTGTTCAT 
CTCCTTTTGA AGACTGCCAA TGAAGGAGGG TCTTTATTAT ATGAACAATT GGGATATAAG 
GCATTTGGAT TAGTTGGAAA GCTTGCAGCA TCTGGATCAA TTACAATGCA GAACATTGGA 
GCTATGTCAA GCTACCTCTT CATAGTGAAA TATGAGTTGC CTTTGGTGAT CCAGGCATTA 
ACGAACATTG AAGATAAAAC TGGATTGTGG TATCTGAACG GGAACTATTT GGTTCTGTTG 
GTGTCATTGG TGGTCATTCT TCCTTTGTCG CTGTTTAGAA ATTTAGGATA TTTGGGATAT 
ACCAGTGGCC TTTCCTTGTT GTGTATGGTG TTCTTTCTGA TTGTGGTCAT TTGCAAGAAA 
TTTCAGGTTC CGTGTCCTGT GGAAGCTGCT TTGATAATTA ACGAAACAAT AAACACCACC 
TTAACACAGC CAACAGCTCT TGTACCTGCT TTGTCACATA ACGTGACTGA AAATGACTCT 
TGCAGACCTC ACTATTTTAT TTTCAACTCA CAGACTGTCT ATGCTGTGCC AATTCTGATC 
TTTTCATTTG TCTGTCATCC TGCTGTTCTT CCCATCTATG AAGAACTGAA AGACCGCAGC 
CGTAGAAGAA TGATGAATGT GTCCAAGATT TCATTTTTTG CTATGTTTCT CATGTATCTG 
CTTGCCGCCC TCTTTGGATA CCTAACATTT TACGAACATG TTGAGTCAGA ATTGCTTCAT 
ACCTACTCTT CTATCTTGGG AACTGATATT CTTCTTCTCA TTGTCCGTCT GGCTGTGTTA 
ATGGCTGTGA CCCTGACAGT ACCAGTAGTT ATTTTCCCAA TCCGGAGTTC TGTAACTCAC 
TTGTTGTGTG CATCAAAAGA TTTCAGTTGG TGGCGTCATA GTCTCATTAC AGTGTCTATC 
TTGGCATTTA CCAATTTACT TGTCATCTTT GTCCCAACTA TTAGGGATAT CTTTGGTTTT 
ATTGGTGCAT CTGCAGCTTC TATGTTGATT TTTATTCTTC CTTCTGCCTT CTATATCAAG 
TTGGTGAAGA AAGAACCTAT GAAATCTGTA CAAAAGATTG GGGCTTTGTT CTTCCTGTTA 
AGTGGTGTAC TGGTGATGAC CGGAAGCATG GCCTTGATTG TTTTGGATTG GGTACACAAT 
GCACCTGGAG GTGGCCATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061849.2
CDS	441..1961
Translation	MKKAEMGRFSISPDEDSSSYSSNSDFNYSYPTKQAALKSHYADVDPENQNFLLESNLGKKKYETEFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGYKAFGLVGKLAASGSITMQNIGAMSSYLFIVKYELPLVIQALTNIEDKTGLWYLNGNYLVLLVSLVVILPLSLFRNLGYLGYTSGLSLLCMVFFLIVVICKKFQVPCPVEAALIINETINTTLTQPTALVPALSHNVTENDSCRPHYFIFNSQTVYAVPILIFSFVCHPAVLPIYEELKDRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYEHVESELLHTYSSILGTDILLLIVRLAVLMAVTLTVPVVIFPIRSSVTHLLCASKDFSWWRHSLITVSILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPSAFYIKLVKKEPMKSVQKIGALFFLLSGVLVMTGSMALIVLDWVHNAPGGGH

Target ORF information:

RefSeq Version	NM_018976.4
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 38 member 2 (SLC38A2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018976.4

ORF Insert Sequence:

ATGAAGAAGG CCGAAATGGG ACGATTCAGT ATTTCCCCGG ATGAAGACAG CAGCAGCTAC 
AGTTCCAACA GCGACTTCAA CTACTCCTAC CCCACCAAGC AAGCTGCTCT GAAAAGCCAT 
TATGCAGATG TAGATCCTGA AAACCAGAAC TTTTTACTTG AATCGAATTT GGGGAAGAAG 
AAGTATGAAA CAGAATTTCA TCCAGGTACT ACTTCCTTTG GAATGTCAGT ATTTAATCTG 
AGCAATGCGA TTGTGGGCAG TGGAATCCTT GGGCTTTCTT ATGCCATGGC TAATACTGGA 
ATTGCTCTTT TTATAATTCT CTTGACATTT GTGTCAATAT TTTCCCTGTA TTCTGTTCAT 
CTCCTTTTGA AGACTGCCAA TGAAGGAGGG TCTTTATTAT ATGAACAATT GGGATATAAG 
GCATTTGGAT TAGTTGGAAA GCTTGCAGCA TCTGGATCAA TTACAATGCA GAACATTGGA 
GCTATGTCAA GCTACCTCTT CATAGTGAAA TATGAGTTGC CTTTGGTGAT CCAGGCATTA 
ACGAACATTG AAGATAAAAC TGGATTGTGG TATCTGAACG GGAACTATTT GGTTCTGTTG 
GTGTCATTGG TGGTCATTCT TCCTTTGTCG CTGTTTAGAA ATTTAGGATA TTTGGGATAT 
ACCAGTGGCC TTTCCTTGTT GTGTATGGTG TTCTTTCTGA TTGTGGTCAT TTGCAAGAAA 
TTTCAGGTTC CGTGTCCTGT GGAAGCTGCT TTGATAATTA ACGAAACAAT AAACACCACC 
TTAACACAGC CAACAGCTCT TGTACCTGCT TTGTCACATA ACGTGACTGA AAATGACTCT 
TGCAGACCTC ACTATTTTAT TTTCAACTCA CAGACTGTCT ATGCTGTGCC AATTCTGATC 
TTTTCATTTG TCTGTCATCC TGCTGTTCTT CCCATCTATG AAGAACTGAA AGACCGCAGC 
CGTAGAAGAA TGATGAATGT GTCCAAGATT TCATTTTTTG CTATGTTTCT CATGTATCTG 
CTTGCCGCCC TCTTTGGATA CCTAACATTT TACGAACATG TTGAGTCAGA ATTGCTTCAT 
ACCTACTCTT CTATCTTGGG AACTGATATT CTTCTTCTCA TTGTCCGTCT GGCTGTGTTA 
ATGGCTGTGA CCCTGACAGT ACCAGTAGTT ATTTTCCCAA TCCGGAGTTC TGTAACTCAC 
TTGTTGTGTG CATCAAAAGA TTTCAGTTGG TGGCGTCATA GTCTCATTAC AGTGTCTATC 
TTGGCATTTA CCAATTTACT TGTCATCTTT GTCCCAACTA TTAGGGATAT CTTTGGTTTT 
ATTGGTGCAT CTGCAGCTTC TATGTTGATT TTTATTCTTC CTTCTGCCTT CTATATCAAG 
TTGGTGAAGA AAGAACCTAT GAAATCTGTA CAAAAGATTG GGGCTTTGTT CTTCCTGTTA 
AGTGGTGTAC TGGTGATGAC CGGAAGCATG GCCTTGATTG TTTTGGATTG GGTACACAAT 
GCACCTGGAG GTGGCCATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC38A2 ( NM_018976.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_061849.2 Homo sapiens solute carrier family 38 member 2 (SLC38A2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09064
Clone ID Related Accession (Same CDS sequence)	NM_018976.4 , NM_018976.5
Accession Version	NM_018976.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1521bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-25
Organism	Homo sapiens(human)
Product	sodium-coupled neutral amino acid transporter 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA725217.1, BC040342.1 and AC025031.30. On Nov 23, 2018 this sequence version replaced NM_018976.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF298897.1, SRR1660803.108319.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000256689.10/ ENSP00000256689.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGAAGG CCGAAATGGG ACGATTCAGT ATTTCCCCGG ATGAAGACAG CAGCAGCTAC 
AGTTCCAACA GCGACTTCAA CTACTCCTAC CCCACCAAGC AAGCTGCTCT GAAAAGCCAT 
TATGCAGATG TAGATCCTGA AAACCAGAAC TTTTTACTTG AATCGAATTT GGGGAAGAAG 
AAGTATGAAA CAGAATTTCA TCCAGGTACT ACTTCCTTTG GAATGTCAGT ATTTAATCTG 
AGCAATGCGA TTGTGGGCAG TGGAATCCTT GGGCTTTCTT ATGCCATGGC TAATACTGGA 
ATTGCTCTTT TTATAATTCT CTTGACATTT GTGTCAATAT TTTCCCTGTA TTCTGTTCAT 
CTCCTTTTGA AGACTGCCAA TGAAGGAGGG TCTTTATTAT ATGAACAATT GGGATATAAG 
GCATTTGGAT TAGTTGGAAA GCTTGCAGCA TCTGGATCAA TTACAATGCA GAACATTGGA 
GCTATGTCAA GCTACCTCTT CATAGTGAAA TATGAGTTGC CTTTGGTGAT CCAGGCATTA 
ACGAACATTG AAGATAAAAC TGGATTGTGG TATCTGAACG GGAACTATTT GGTTCTGTTG 
GTGTCATTGG TGGTCATTCT TCCTTTGTCG CTGTTTAGAA ATTTAGGATA TTTGGGATAT 
ACCAGTGGCC TTTCCTTGTT GTGTATGGTG TTCTTTCTGA TTGTGGTCAT TTGCAAGAAA 
TTTCAGGTTC CGTGTCCTGT GGAAGCTGCT TTGATAATTA ACGAAACAAT AAACACCACC 
TTAACACAGC CAACAGCTCT TGTACCTGCT TTGTCACATA ACGTGACTGA AAATGACTCT 
TGCAGACCTC ACTATTTTAT TTTCAACTCA CAGACTGTCT ATGCTGTGCC AATTCTGATC 
TTTTCATTTG TCTGTCATCC TGCTGTTCTT CCCATCTATG AAGAACTGAA AGACCGCAGC 
CGTAGAAGAA TGATGAATGT GTCCAAGATT TCATTTTTTG CTATGTTTCT CATGTATCTG 
CTTGCCGCCC TCTTTGGATA CCTAACATTT TACGAACATG TTGAGTCAGA ATTGCTTCAT 
ACCTACTCTT CTATCTTGGG AACTGATATT CTTCTTCTCA TTGTCCGTCT GGCTGTGTTA 
ATGGCTGTGA CCCTGACAGT ACCAGTAGTT ATTTTCCCAA TCCGGAGTTC TGTAACTCAC 
TTGTTGTGTG CATCAAAAGA TTTCAGTTGG TGGCGTCATA GTCTCATTAC AGTGTCTATC 
TTGGCATTTA CCAATTTACT TGTCATCTTT GTCCCAACTA TTAGGGATAT CTTTGGTTTT 
ATTGGTGCAT CTGCAGCTTC TATGTTGATT TTTATTCTTC CTTCTGCCTT CTATATCAAG 
TTGGTGAAGA AAGAACCTAT GAAATCTGTA CAAAAGATTG GGGCTTTGTT CTTCCTGTTA 
AGTGGTGTAC TGGTGATGAC CGGAAGCATG GCCTTGATTG TTTTGGATTG GGTACACAAT 
GCACCTGGAG GTGGCCATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061849.2
CDS	352..1872
Translation	MKKAEMGRFSISPDEDSSSYSSNSDFNYSYPTKQAALKSHYADVDPENQNFLLESNLGKKKYETEFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGYKAFGLVGKLAASGSITMQNIGAMSSYLFIVKYELPLVIQALTNIEDKTGLWYLNGNYLVLLVSLVVILPLSLFRNLGYLGYTSGLSLLCMVFFLIVVICKKFQVPCPVEAALIINETINTTLTQPTALVPALSHNVTENDSCRPHYFIFNSQTVYAVPILIFSFVCHPAVLPIYEELKDRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYEHVESELLHTYSSILGTDILLLIVRLAVLMAVTLTVPVVIFPIRSSVTHLLCASKDFSWWRHSLITVSILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPSAFYIKLVKKEPMKSVQKIGALFFLLSGVLVMTGSMALIVLDWVHNAPGGGH

Target ORF information:

RefSeq Version	NM_018976.5
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 38 member 2 (SLC38A2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018976.5

ORF Insert Sequence:

ATGAAGAAGG CCGAAATGGG ACGATTCAGT ATTTCCCCGG ATGAAGACAG CAGCAGCTAC 
AGTTCCAACA GCGACTTCAA CTACTCCTAC CCCACCAAGC AAGCTGCTCT GAAAAGCCAT 
TATGCAGATG TAGATCCTGA AAACCAGAAC TTTTTACTTG AATCGAATTT GGGGAAGAAG 
AAGTATGAAA CAGAATTTCA TCCAGGTACT ACTTCCTTTG GAATGTCAGT ATTTAATCTG 
AGCAATGCGA TTGTGGGCAG TGGAATCCTT GGGCTTTCTT ATGCCATGGC TAATACTGGA 
ATTGCTCTTT TTATAATTCT CTTGACATTT GTGTCAATAT TTTCCCTGTA TTCTGTTCAT 
CTCCTTTTGA AGACTGCCAA TGAAGGAGGG TCTTTATTAT ATGAACAATT GGGATATAAG 
GCATTTGGAT TAGTTGGAAA GCTTGCAGCA TCTGGATCAA TTACAATGCA GAACATTGGA 
GCTATGTCAA GCTACCTCTT CATAGTGAAA TATGAGTTGC CTTTGGTGAT CCAGGCATTA 
ACGAACATTG AAGATAAAAC TGGATTGTGG TATCTGAACG GGAACTATTT GGTTCTGTTG 
GTGTCATTGG TGGTCATTCT TCCTTTGTCG CTGTTTAGAA ATTTAGGATA TTTGGGATAT 
ACCAGTGGCC TTTCCTTGTT GTGTATGGTG TTCTTTCTGA TTGTGGTCAT TTGCAAGAAA 
TTTCAGGTTC CGTGTCCTGT GGAAGCTGCT TTGATAATTA ACGAAACAAT AAACACCACC 
TTAACACAGC CAACAGCTCT TGTACCTGCT TTGTCACATA ACGTGACTGA AAATGACTCT 
TGCAGACCTC ACTATTTTAT TTTCAACTCA CAGACTGTCT ATGCTGTGCC AATTCTGATC 
TTTTCATTTG TCTGTCATCC TGCTGTTCTT CCCATCTATG AAGAACTGAA AGACCGCAGC 
CGTAGAAGAA TGATGAATGT GTCCAAGATT TCATTTTTTG CTATGTTTCT CATGTATCTG 
CTTGCCGCCC TCTTTGGATA CCTAACATTT TACGAACATG TTGAGTCAGA ATTGCTTCAT 
ACCTACTCTT CTATCTTGGG AACTGATATT CTTCTTCTCA TTGTCCGTCT GGCTGTGTTA 
ATGGCTGTGA CCCTGACAGT ACCAGTAGTT ATTTTCCCAA TCCGGAGTTC TGTAACTCAC 
TTGTTGTGTG CATCAAAAGA TTTCAGTTGG TGGCGTCATA GTCTCATTAC AGTGTCTATC 
TTGGCATTTA CCAATTTACT TGTCATCTTT GTCCCAACTA TTAGGGATAT CTTTGGTTTT 
ATTGGTGCAT CTGCAGCTTC TATGTTGATT TTTATTCTTC CTTCTGCCTT CTATATCAAG 
TTGGTGAAGA AAGAACCTAT GAAATCTGTA CAAAAGATTG GGGCTTTGTT CTTCCTGTTA 
AGTGGTGTAC TGGTGATGAC CGGAAGCATG GCCTTGATTG TTTTGGATTG GGTACACAAT 
GCACCTGGAG GTGGCCATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC38A2 ( NM_001307936.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001294865.1 Homo sapiens solute carrier family 38 member 2 (SLC38A2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu46643
Clone ID Related Accession (Same CDS sequence)	NM_001307936.1 , NM_001307936.2
Accession Version	NM_001307936.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-30
Organism	Homo sapiens(human)
Product	sodium-coupled neutral amino acid transporter 2 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA725217.1, AK001700.1, BC040342.1 and BC029379.1. On Apr 17, 2015 this sequence version replaced XM_005268983.2. Transcript Variant: This variant (2) lacks an exon in its 5' coding region compared to variant 1. This variant represents translation initiation at an alternate start codon compared to variant 1; the 5'-most initiation codon, as used in variant 1, is associated with a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning may allow translation initiation at the alternate start codon to encode an isoform (2) that has a distinct and shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.79605.1, SRR1660803.165170.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAACAGA ATTTAATTCT CTTGACATTT GTGTCAATAT TTTCCCTGTA TTCTGTTCAT 
CTCCTTTTGA AGACTGCCAA TGAAGGAGGG TCTTTATTAT ATGAACAATT GGGATATAAG 
GCATTTGGAT TAGTTGGAAA GCTTGCAGCA TCTGGATCAA TTACAATGCA GAACATTGGA 
GCTATGTCAA GCTACCTCTT CATAGTGAAA TATGAGTTGC CTTTGGTGAT CCAGGCATTA 
ACGAACATTG AAGATAAAAC TGGATTGTGG TATCTGAACG GGAACTATTT GGTTCTGTTG 
GTGTCATTGG TGGTCATTCT TCCTTTGTCG CTGTTTAGAA ATTTAGGATA TTTGGGATAT 
ACCAGTGGCC TTTCCTTGTT GTGTATGGTG TTCTTTCTGA TTGTGGTCAT TTGCAAGAAA 
TTTCAGGTTC CGTGTCCTGT GGAAGCTGCT TTGATAATTA ACGAAACAAT AAACACCACC 
TTAACACAGC CAACAGCTCT TGTACCTGCT TTGTCACATA ACGTGACTGA AAATGACTCT 
TGCAGACCTC ACTATTTTAT TTTCAACTCA CAGACTGTCT ATGCTGTGCC AATTCTGATC 
TTTTCATTTG TCTGTCATCC TGCTGTTCTT CCCATCTATG AAGAACTGAA AGACCGCAGC 
CGTAGAAGAA TGATGAATGT GTCCAAGATT TCATTTTTTG CTATGTTTCT CATGTATCTG 
CTTGCCGCCC TCTTTGGATA CCTAACATTT TACGAACATG TTGAGTCAGA ATTGCTTCAT 
ACCTACTCTT CTATCTTGGG AACTGATATT CTTCTTCTCA TTGTCCGTCT GGCTGTGTTA 
ATGGCTGTGA CCCTGACAGT ACCAGTAGTT ATTTTCCCAA TCCGGAGTTC TGTAACTCAC 
TTGTTGTGTG CATCAAAAGA TTTCAGTTGG TGGCGTCATA GTCTCATTAC AGTGTCTATC 
TTGGCATTTA CCAATTTACT TGTCATCTTT GTCCCAACTA TTAGGGATAT CTTTGGTTTT 
ATTGGTGCAT CTGCAGCTTC TATGTTGATT TTTATTCTTC CTTCTGCCTT CTATATCAAG 
TTGGTGAAGA AAGAACCTAT GAAATCTGTA CAAAAGATTG GGGCTTTGTT CTTCCTGTTA 
AGTGGTGTAC TGGTGATGAC CGGAAGCATG GCCTTGATTG TTTTGGATTG GGTACACAAT 
GCACCTGGAG GTGGCCATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001294865.1
CDS	625..1845
Translation	MKQNLILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGYKAFGLVGKLAASGSITMQNIGAMSSYLFIVKYELPLVIQALTNIEDKTGLWYLNGNYLVLLVSLVVILPLSLFRNLGYLGYTSGLSLLCMVFFLIVVICKKFQVPCPVEAALIINETINTTLTQPTALVPALSHNVTENDSCRPHYFIFNSQTVYAVPILIFSFVCHPAVLPIYEELKDRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYEHVESELLHTYSSILGTDILLLIVRLAVLMAVTLTVPVVIFPIRSSVTHLLCASKDFSWWRHSLITVSILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPSAFYIKLVKKEPMKSVQKIGALFFLLSGVLVMTGSMALIVLDWVHNAPGGGH

Target ORF information:

RefSeq Version	NM_001307936.1
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 38 member 2 (SLC38A2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001307936.1

ORF Insert Sequence:

ATGAAACAGA ATTTAATTCT CTTGACATTT GTGTCAATAT TTTCCCTGTA TTCTGTTCAT 
CTCCTTTTGA AGACTGCCAA TGAAGGAGGG TCTTTATTAT ATGAACAATT GGGATATAAG 
GCATTTGGAT TAGTTGGAAA GCTTGCAGCA TCTGGATCAA TTACAATGCA GAACATTGGA 
GCTATGTCAA GCTACCTCTT CATAGTGAAA TATGAGTTGC CTTTGGTGAT CCAGGCATTA 
ACGAACATTG AAGATAAAAC TGGATTGTGG TATCTGAACG GGAACTATTT GGTTCTGTTG 
GTGTCATTGG TGGTCATTCT TCCTTTGTCG CTGTTTAGAA ATTTAGGATA TTTGGGATAT 
ACCAGTGGCC TTTCCTTGTT GTGTATGGTG TTCTTTCTGA TTGTGGTCAT TTGCAAGAAA 
TTTCAGGTTC CGTGTCCTGT GGAAGCTGCT TTGATAATTA ACGAAACAAT AAACACCACC 
TTAACACAGC CAACAGCTCT TGTACCTGCT TTGTCACATA ACGTGACTGA AAATGACTCT 
TGCAGACCTC ACTATTTTAT TTTCAACTCA CAGACTGTCT ATGCTGTGCC AATTCTGATC 
TTTTCATTTG TCTGTCATCC TGCTGTTCTT CCCATCTATG AAGAACTGAA AGACCGCAGC 
CGTAGAAGAA TGATGAATGT GTCCAAGATT TCATTTTTTG CTATGTTTCT CATGTATCTG 
CTTGCCGCCC TCTTTGGATA CCTAACATTT TACGAACATG TTGAGTCAGA ATTGCTTCAT 
ACCTACTCTT CTATCTTGGG AACTGATATT CTTCTTCTCA TTGTCCGTCT GGCTGTGTTA 
ATGGCTGTGA CCCTGACAGT ACCAGTAGTT ATTTTCCCAA TCCGGAGTTC TGTAACTCAC 
TTGTTGTGTG CATCAAAAGA TTTCAGTTGG TGGCGTCATA GTCTCATTAC AGTGTCTATC 
TTGGCATTTA CCAATTTACT TGTCATCTTT GTCCCAACTA TTAGGGATAT CTTTGGTTTT 
ATTGGTGCAT CTGCAGCTTC TATGTTGATT TTTATTCTTC CTTCTGCCTT CTATATCAAG 
TTGGTGAAGA AAGAACCTAT GAAATCTGTA CAAAAGATTG GGGCTTTGTT CTTCCTGTTA 
AGTGGTGTAC TGGTGATGAC CGGAAGCATG GCCTTGATTG TTTTGGATTG GGTACACAAT 
GCACCTGGAG GTGGCCATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC38A2 ( NM_001307936.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001294865.1 Homo sapiens solute carrier family 38 member 2 (SLC38A2), transcript variant 2, mRNA.

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CloneID	OHu46643
Clone ID Related Accession (Same CDS sequence)	NM_001307936.1 , NM_001307936.2
Accession Version	NM_001307936.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-25
Organism	Homo sapiens(human)
Product	sodium-coupled neutral amino acid transporter 2 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA725217.1, AK001700.1, BC040342.1 and BC029379.1. On Jun 1, 2019 this sequence version replaced NM_001307936.1. Transcript Variant: This variant (2) lacks an exon in its 5' coding region compared to variant 1. This variant represents translation initiation at an alternate start codon compared to variant 1; the 5'-most initiation codon, as used in variant 1, is associated with a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning may allow translation initiation at the alternate start codon to encode an isoform (2) that has a distinct and shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.221283.1, SRR1803615.124766.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAACAGA ATTTAATTCT CTTGACATTT GTGTCAATAT TTTCCCTGTA TTCTGTTCAT 
CTCCTTTTGA AGACTGCCAA TGAAGGAGGG TCTTTATTAT ATGAACAATT GGGATATAAG 
GCATTTGGAT TAGTTGGAAA GCTTGCAGCA TCTGGATCAA TTACAATGCA GAACATTGGA 
GCTATGTCAA GCTACCTCTT CATAGTGAAA TATGAGTTGC CTTTGGTGAT CCAGGCATTA 
ACGAACATTG AAGATAAAAC TGGATTGTGG TATCTGAACG GGAACTATTT GGTTCTGTTG 
GTGTCATTGG TGGTCATTCT TCCTTTGTCG CTGTTTAGAA ATTTAGGATA TTTGGGATAT 
ACCAGTGGCC TTTCCTTGTT GTGTATGGTG TTCTTTCTGA TTGTGGTCAT TTGCAAGAAA 
TTTCAGGTTC CGTGTCCTGT GGAAGCTGCT TTGATAATTA ACGAAACAAT AAACACCACC 
TTAACACAGC CAACAGCTCT TGTACCTGCT TTGTCACATA ACGTGACTGA AAATGACTCT 
TGCAGACCTC ACTATTTTAT TTTCAACTCA CAGACTGTCT ATGCTGTGCC AATTCTGATC 
TTTTCATTTG TCTGTCATCC TGCTGTTCTT CCCATCTATG AAGAACTGAA AGACCGCAGC 
CGTAGAAGAA TGATGAATGT GTCCAAGATT TCATTTTTTG CTATGTTTCT CATGTATCTG 
CTTGCCGCCC TCTTTGGATA CCTAACATTT TACGAACATG TTGAGTCAGA ATTGCTTCAT 
ACCTACTCTT CTATCTTGGG AACTGATATT CTTCTTCTCA TTGTCCGTCT GGCTGTGTTA 
ATGGCTGTGA CCCTGACAGT ACCAGTAGTT ATTTTCCCAA TCCGGAGTTC TGTAACTCAC 
TTGTTGTGTG CATCAAAAGA TTTCAGTTGG TGGCGTCATA GTCTCATTAC AGTGTCTATC 
TTGGCATTTA CCAATTTACT TGTCATCTTT GTCCCAACTA TTAGGGATAT CTTTGGTTTT 
ATTGGTGCAT CTGCAGCTTC TATGTTGATT TTTATTCTTC CTTCTGCCTT CTATATCAAG 
TTGGTGAAGA AAGAACCTAT GAAATCTGTA CAAAAGATTG GGGCTTTGTT CTTCCTGTTA 
AGTGGTGTAC TGGTGATGAC CGGAAGCATG GCCTTGATTG TTTTGGATTG GGTACACAAT 
GCACCTGGAG GTGGCCATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001294865.1
CDS	536..1756
Translation	MKQNLILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGYKAFGLVGKLAASGSITMQNIGAMSSYLFIVKYELPLVIQALTNIEDKTGLWYLNGNYLVLLVSLVVILPLSLFRNLGYLGYTSGLSLLCMVFFLIVVICKKFQVPCPVEAALIINETINTTLTQPTALVPALSHNVTENDSCRPHYFIFNSQTVYAVPILIFSFVCHPAVLPIYEELKDRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYEHVESELLHTYSSILGTDILLLIVRLAVLMAVTLTVPVVIFPIRSSVTHLLCASKDFSWWRHSLITVSILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPSAFYIKLVKKEPMKSVQKIGALFFLLSGVLVMTGSMALIVLDWVHNAPGGGH

Target ORF information:

RefSeq Version	NM_001307936.2
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 38 member 2 (SLC38A2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001307936.2

ORF Insert Sequence:

ATGAAACAGA ATTTAATTCT CTTGACATTT GTGTCAATAT TTTCCCTGTA TTCTGTTCAT 
CTCCTTTTGA AGACTGCCAA TGAAGGAGGG TCTTTATTAT ATGAACAATT GGGATATAAG 
GCATTTGGAT TAGTTGGAAA GCTTGCAGCA TCTGGATCAA TTACAATGCA GAACATTGGA 
GCTATGTCAA GCTACCTCTT CATAGTGAAA TATGAGTTGC CTTTGGTGAT CCAGGCATTA 
ACGAACATTG AAGATAAAAC TGGATTGTGG TATCTGAACG GGAACTATTT GGTTCTGTTG 
GTGTCATTGG TGGTCATTCT TCCTTTGTCG CTGTTTAGAA ATTTAGGATA TTTGGGATAT 
ACCAGTGGCC TTTCCTTGTT GTGTATGGTG TTCTTTCTGA TTGTGGTCAT TTGCAAGAAA 
TTTCAGGTTC CGTGTCCTGT GGAAGCTGCT TTGATAATTA ACGAAACAAT AAACACCACC 
TTAACACAGC CAACAGCTCT TGTACCTGCT TTGTCACATA ACGTGACTGA AAATGACTCT 
TGCAGACCTC ACTATTTTAT TTTCAACTCA CAGACTGTCT ATGCTGTGCC AATTCTGATC 
TTTTCATTTG TCTGTCATCC TGCTGTTCTT CCCATCTATG AAGAACTGAA AGACCGCAGC 
CGTAGAAGAA TGATGAATGT GTCCAAGATT TCATTTTTTG CTATGTTTCT CATGTATCTG 
CTTGCCGCCC TCTTTGGATA CCTAACATTT TACGAACATG TTGAGTCAGA ATTGCTTCAT 
ACCTACTCTT CTATCTTGGG AACTGATATT CTTCTTCTCA TTGTCCGTCT GGCTGTGTTA 
ATGGCTGTGA CCCTGACAGT ACCAGTAGTT ATTTTCCCAA TCCGGAGTTC TGTAACTCAC 
TTGTTGTGTG CATCAAAAGA TTTCAGTTGG TGGCGTCATA GTCTCATTAC AGTGTCTATC 
TTGGCATTTA CCAATTTACT TGTCATCTTT GTCCCAACTA TTAGGGATAT CTTTGGTTTT 
ATTGGTGCAT CTGCAGCTTC TATGTTGATT TTTATTCTTC CTTCTGCCTT CTATATCAAG 
TTGGTGAAGA AAGAACCTAT GAAATCTGTA CAAAAGATTG GGGCTTTGTT CTTCCTGTTA 
AGTGGTGTAC TGGTGATGAC CGGAAGCATG GCCTTGATTG TTTTGGATTG GGTACACAAT 
GCACCTGGAG GTGGCCATTA A