tcf7l2 cDNA ORF clone, Danio rerio(zebrafish)

Wnt/?-catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating Notch activity.
So J, Khaliq M, Evason K, Ninov N, Martin BL, Stainier DYR, Shin D
Hepatology (Baltimore, Md.)(2017 Dec)

Tcf7l2 plays pleiotropic roles in the control of glucose homeostasis, pancreas morphology, vascularization and regeneration.
Facchinello N, Tarife?o-Saldivia E, Grisan E, Schiavone M, Peron M, Mongera A, Ek O, Schmitner N, Meyer D, Peers B, Tiso N, Argenton F
Scientific reports7(1)9605(2017 Aug)

Tcf7l2 is essential for lateralized fate selection by habenular neurons that can differentiate along two alternative pathways, thereby leading to major neural circuit asymmetries.
Title: Tcf7l2 is required for left-right asymmetric differentiation of habenular neurons.

Dorsal and ventral habenulae develop in different regions of prosomere 2. In the process of ventral habenula formation, functional tcf7l2 gene activity is required and in its absence, ventral habenular neurons do not develop.
Title: The ventral habenulae of zebrafish develop in prosomere 2 dependent on Tcf7l2 function.

This study reveals that Tcf4 (tcf7l2) is the major effector of Wnt signaling in the intestine during zebrafish organogenesis.
Title: T-cell factor 4 (tcf7l2) is the main effector of Wnt signaling during zebrafish intestine organogenesis.

Study underscores the involvement of Tcf4 in maintaining proliferative self-renewal in the intestine throughout life.
Title: T-cell factor 4 (Tcf7l2) maintains proliferative compartments in zebrafish intestine.

In embryos, the tcf4 gene is highly regulated at the level of RNA splicing such that the variant proteins that are produced contain or lack domains proposed to be essential in repression or activation of transcription.
Title: Expression and splice variant analysis of the zebrafish tcf4 transcription factor.