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Recombinant Antibody Service Selection Guide

One stop service from sequence to recombinant atibody

Recombinant Antibody Service Selection Guide

With solid expertise in recombinant antibody (rAb) production techniques, GenScript provides a comprehensive rAb service portfolio. Choose from services that deliver microgram to gram quantities of pure rAb for each stage of your Ab drug discovery program

Use chart to quickly determine which GenScript packages are the best match for your application.

Purpose	Service	Production Type	Volume	Antibody quantity	Timeline	Guiding Price per unit	QC standard
Screening	HTP Gene to Antibody Production	HTP Transient Expression	1ml-50ml	50μg-1mg	18 business days	~$300 per variant*	Titer: ELISA Purity: SDS-PAGE -85% Quantitation: UV A280
Candidate validation	MamPower™ guaranteed recombinant antibody production	Transient Expression in Shaking flask	0.1L-1L	4mg-100mg	3-4 weeks	$30-$500/mg antibody^#	Titer: ELISA Purity: SDS-PAGE -90% Quantitation: UV A280
In vitro efficacy	MamPower™ guaranteed recombinant antibody production	Transient Expression in Shaking flask	1L-10L	40mg-1g	4-5 weeks	$12-75/mg antibody^#	Titer: ELISA Purity: SDS-PAGE -95%; HPLC -95% Quantitation: UV A280 Endotoxin:<1EU/mg
In vitro efficacy	Large scale recombinant antibody production	Transient Expression in Shaking flask	1L-10L	40mg-1g	4-5 weeks	$12-75/mg antibody^#
In vivo efficacy	Large scale recombinant antibody production	Transient Expression in Wavebag	10L-25L	400mg-2.5g	6-8 weeks	$10-30/mg antibody^#	Titer: ELISA Purity: SDS-PAGE -95%/99%; HPLC -95%/99% Quantitation: UV A280 Endotoxin:<1EU/mg or <0.1EU/mg
In vivo efficacy	Custom Services	Wavebag cell pool	10L-25L	1g-12.5g	12-14 weeks	$3.2-22/mg antibody^#
Safety test with GLP	Custom Services	Bioreactor cell pool	25L-100L	2.5g-50g	12-16 weeks	$2.4-16/mg antibody^#	Titer: ELISA Purity:SDS-PAGE -95%/99%; HPLC -95%/99% Quantitation: UV A280 Endotoxin:<1EU/mg or <0.1EU/mg Identification: MS
Safety test with GLP	Gram Level Bioproduction cell line service	Bioreactor cell line	10L-100L	10g-100g	24-28 weeks	$1.5-6/mg antibody^#

QC data: SDS-PAGE and/or HPLC will be performed to determine rAb purity. A280 will be used to measure rAb concentration. MS will be used for identification. GenScript uses The Endosafe^®-PTS™ endotoxin testing system from Charles River Laboratories, for rapid endotoxin detection.

*Not including gene synthesis
^#Including gene synthesis

To request a quote, click on the quote button and follow the steps described. For more information about our other services, please visit our recombinant protein services main page or contact us using the information listed below.

Our services include:

High Throughput expression and purification of recombinant antibodies (1ml-40ml)

Transient expression in HEK293 or CHO cells and 1-step purification using Protein A resin

Lab-scale transient expression in shaking flasks (100ml-10L)

Transient antibody expression in mammalian cells, both HEK293 and CHO cell lines

Mid-scale antibody expression in wavebag (10L-25L)

Transient (HEK293/CHO) or Stable pool production (CHO cells)

Large scale antibody expression in wavebag or S.U.B bioreactor (varies)

Transient or Stable pool production (CHO cells, >25 L), or Stable cell line production (CHO-GS, >10 L, deliver the cell line)

Characterization services with LC-MS

For QC and verification of biologics