Cd300a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cd300a
Entrez Gene ID	501736
Full Name	Cd300a molecule
Synonyms	CLM-8
General protein information	Preferred Names Cd300a molecule Names CMRF35-like molecule 8 CD300 antigen-like family member A immune inhibitory receptor CD300A
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q32.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001205348.1	NP_001192277.1	CMRF35-like molecule 8 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CD300A	XP_005624196.1
Mus musculus (house mouse)	Cd300a	NP_739564.1
	LOC702540	XP_001090848.2
Bos taurus (cattle)	CD300A	NP_001179385.1
Pan troglodytes (chimpanzee)	CD300A	XP_523707.2
Rattus norvegicus (Norway rat)	Cd300a	NP_001192277.1
Homo sapiens (human)	CD300A	NP_009192.2

Gene Ontology
Bibliography

Related articles in PubMed

Human CD300a binds to phosphatidylethanolamine and phosphatidylserine, and modulates the phagocytosis of dead cells.
Simhadri VR, Andersen JF, Calvo E, Choi SC, Coligan JE, Borrego F
Blood119(12)2799-809(2012 Mar)

CD300a and CD300f differentially regulate the MyD88 and TRIF-mediated TLR signalling pathways through activation of SHP-1 and/or SHP-2 in human monocytic cell lines.
Kim EJ, Lee SM, Suk K, Lee WH
Immunology135(3)226-35(2012 Mar)

Differential expression of CD300a/c on human TH1 and TH17 cells.
Simhadri VR, Mariano JL, Zhou Q, DeBell KE, Borrego F
BMC immunology1262(2011 Nov)

CD300a is expressed on human B cells, modulates BCR-mediated signaling, and its expression is down-regulated in HIV infection.
Silva R, Moir S, Kardava L, Debell K, Simhadri VR, Ferrando-Mart?nez S, Leal M, Pe?a J, Coligan JE, Borrego F
Blood117(22)5870-80(2011 Jun)

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W
Immunology and cell biology88(8)851-6(2010 Nov-Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cd300a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd300a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42805	NM_001205348.1 Latest version!	Rattus norvegicus Cd300a molecule (Cd300a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cd300a ( NM_001205348.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001192277.1 Rattus norvegicus Cd300a molecule (Cd300a), mRNA.

Price & Availability↑

CloneID	ORa42805
Clone ID Related Accession (Same CDS sequence)	NM_001205348.1
Accession Version	NM_001205348.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 933bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	CMRF35-like molecule 8 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FQ230743.1, EF199812.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297, SAMEA2689594 [ECO:0000348] ##Evidence-Data-END##

ATGACCCAGC TGGCCTCAGC TGTGTGGCTG CCCACGCTGT TGCTGCTGCT GCTTTTCTGG 
GTTCCAGGCT GTGTCCCTCT TCGTGGCCCC AGCAGTGTGA CAGGAACTGT GGGGGAGTCC 
CTGAACGTGA CTTGTCAGTA TGAGGAGAGA TTCAAGATGA ATAAGAAATA CTGGTGCAGA 
GGGTCACTTG TTCTACTTTG CAAAGATATT GTCAAGACCG GAGGCTCAGA AGAAGCTAGG 
AATGGCCGAG TGTCCATCAG GGACGATCGA GACAACCTGA CCTTCACAGT GACCTTGCAG 
AACCTCACGC TGGAGGATGC AGGCACCTAC ATGTGTGCGG TGGATATACC ATTGATCGAT 
CACTCCTTCA AGGTTGAATT GTCTGTGGTC CCAGGTAACA TCCCAGTTTC ATCTCCAGGA 
ACAACACGAG AGACAACTGT GGTGCCCACC AGCTTCTCTA CCAAGGGTCC CACCCAAGGA 
TCCATCCCAG AGGGGCACCA TGAACATTAT GAGCCCCAGG GCTTGAGTCT CCCAGTGCTG 
CTGTCCGTGT TAGCTCTCTT GCTGTTGCTG TTGGTGGGGA CCTCTCTGCT GGCCTGGAGG 
ATGTTCCAGA AGCGGTCAGT CAAAGCTGAT AAGCACCCAG AGATGTCCCA GAACCTCAGA 
CAGGCCGAGG AGCAGAGTGA ATCCCAGTAT GTCAATCTGC AGCTGCACAC GTTGCCCCTG 
AGGGAAGAGC CGGTGCCACC AAGTCAGGTG GAGGTAGAAT ACAGCACACT GGCATTACCT 
CAGGAAGAGC TCCATTATAC ATCCGTGGTA TTCGACTCTC AGAGGCAGAA TTCTCATGCC 
AATGGGGATC CCCCTTGTCA ATCTCCGGAC CAAAAAACAG AGTACAGTGA GATCCGGAAG 
CCCAGAGAAG GTCTCTCTGA CCCTCACCCG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001192277.1
CDS	326..1258
Translation	MTQLASAVWLPTLLLLLLFWVPGCVPLRGPSSVTGTVGESLNVTCQYEERFKMNKKYWCRGSLVLLCKDIVKTGGSEEARNGRVSIRDDRDNLTFTVTLQNLTLEDAGTYMCAVDIPLIDHSFKVELSVVPGNIPVSSPGTTRETTVVPTSFSTKGPTQGSIPEGHHEHYEPQGLSLPVLLSVLALLLLLLVGTSLLAWRMFQKRSVKADKHPEMSQNLRQAEEQSESQYVNLQLHTLPLREEPVPPSQVEVEYSTLALPQEELHYTSVVFDSQRQNSHANGDPPCQSPDQKTEYSEIRKPREGLSDPHP

Target ORF information:

RefSeq Version	NM_001205348.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Cd300a molecule (Cd300a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001205348.1

ORF Insert Sequence:

ATGACCCAGC TGGCCTCAGC TGTGTGGCTG CCCACGCTGT TGCTGCTGCT GCTTTTCTGG 
GTTCCAGGCT GTGTCCCTCT TCGTGGCCCC AGCAGTGTGA CAGGAACTGT GGGGGAGTCC 
CTGAACGTGA CTTGTCAGTA TGAGGAGAGA TTCAAGATGA ATAAGAAATA CTGGTGCAGA 
GGGTCACTTG TTCTACTTTG CAAAGATATT GTCAAGACCG GAGGCTCAGA AGAAGCTAGG 
AATGGCCGAG TGTCCATCAG GGACGATCGA GACAACCTGA CCTTCACAGT GACCTTGCAG 
AACCTCACGC TGGAGGATGC AGGCACCTAC ATGTGTGCGG TGGATATACC ATTGATCGAT 
CACTCCTTCA AGGTTGAATT GTCTGTGGTC CCAGGTAACA TCCCAGTTTC ATCTCCAGGA 
ACAACACGAG AGACAACTGT GGTGCCCACC AGCTTCTCTA CCAAGGGTCC CACCCAAGGA 
TCCATCCCAG AGGGGCACCA TGAACATTAT GAGCCCCAGG GCTTGAGTCT CCCAGTGCTG 
CTGTCCGTGT TAGCTCTCTT GCTGTTGCTG TTGGTGGGGA CCTCTCTGCT GGCCTGGAGG 
ATGTTCCAGA AGCGGTCAGT CAAAGCTGAT AAGCACCCAG AGATGTCCCA GAACCTCAGA 
CAGGCCGAGG AGCAGAGTGA ATCCCAGTAT GTCAATCTGC AGCTGCACAC GTTGCCCCTG 
AGGGAAGAGC CGGTGCCACC AAGTCAGGTG GAGGTAGAAT ACAGCACACT GGCATTACCT 
CAGGAAGAGC TCCATTATAC ATCCGTGGTA TTCGACTCTC AGAGGCAGAA TTCTCATGCC 
AATGGGGATC CCCCTTGTCA ATCTCCGGAC CAAAAAACAG AGTACAGTGA GATCCGGAAG 
CCCAGAGAAG GTCTCTCTGA CCCTCACCCG TGA