Slc4a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc4a1
Entrez Gene ID	24779
Full Name	solute carrier family 4 member 1
General protein information	Preferred Names solute carrier family 4 member 1 Names band 3 anion transport protein AE 1 Solute carrier family 4, member 1, anion exchange protein 1 (kidney band 3) anion exchange protein 1 anion exchanger 1 solute carrier family 4 (anion exchanger), member 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q32.1
Summary	a transporter; functions as a chloride/carbonate exchanger and binds to components of the cytoskeleton [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012651.2	NP_036783.2	band 3 anion transport protein
XM_008767946.2	XP_008766168.1	band 3 anion transport protein isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SLC4A1	NP_001041496.1
Gallus gallus (chicken)	SLC4A1	NP_990853.1
Homo sapiens (human)	SLC4A1	NP_000333.1
Mus musculus (house mouse)	Slc4a1	NP_035533.1
Pan troglodytes (chimpanzee)	SLC4A1	XP_001151353.2
Rattus norvegicus (Norway rat)	Slc4a1	NP_036783.2
Xenopus tropicalis (tropical clawed frog)	slc4a1	XP_002935581.2
Bos taurus (cattle)	SLC4A1	NP_851379.1

Gene Ontology
Bibliography

Related articles in PubMed

Cluster of erythrocyte band 3: a potential molecular target of exhaustive exercise-induced dysfunction of erythrocyte deformability.
Xiong Y, Li Y, Xiong Y, Zhao Y, Tang F, Wang X
Canadian journal of physiology and pharmacology91(12)1127-34(2013 Dec)

A substrate access tunnel in the cytosolic domain is not an essential feature of the solute carrier 4 (SLC4) family of bicarbonate transporters.
Shnitsar V, Li J, Li X, Calmettes C, Basu A, Casey JR, Moraes TF, Reithmeier RA
The Journal of biological chemistry288(47)33848-60(2013 Nov)

Activity and distribution of intracellular carbonic anhydrase II and their effects on the transport activity of anion exchanger AE1/SLC4A1.
Al-Samir S, Papadopoulos S, Scheibe RJ, Mei?ner JD, Cartron JP, Sly WS, Alper SL, Gros G, Endeward V
The Journal of physiology591(20)4963-82(2013 Oct)

Natural antiband 3 antibodies in patients with sickle cell disease.
Villaescusa R, Arce AA, Lalanne-Mistrih ML, Lamarre Y, Hierso R, Hern?ndez C, Hardy-Dessources MD,
Comptes rendus biologies336(3)173-6(2013 Mar)

Tropical distal renal tubular acidosis: clinical and epidemiological studies in 78 patients.
Khositseth S, Bruce LJ, Walsh SB, Bawazir WM, Ogle GD, Unwin RJ, Thong MK, Sinha R, Choo KE, Chartapisak W, Kingwatanakul P, Sumboonnanonda A, Vasuvattakul S, Yenchitsomanus P, Wrong O
QJM : monthly journal of the Association of Physicians105(9)861-77(2012 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

in the structure and function of erythrocyte band 3.
Title: Cluster of erythrocyte band 3: a potential molecular target of exhaustive exercise-induced dysfunction of erythrocyte deformability.

The following Slc4a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc4a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13450	NM_012651.2 Latest version!	Rattus norvegicus solute carrier family 4 member 1 (Diego blood group) (Slc4a1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa33645	XM_008767946.2 Latest version!	Rattus norvegicus solute carrier family 4 (anion exchanger), member 1 (Slc4a1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc4a1 ( NM_012651.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036783.2 Rattus norvegicus solute carrier family 4 member 1 (Diego blood group) (Slc4a1), mRNA.

Price & Availability↑

CloneID	ORa13450
Clone ID Related Accession (Same CDS sequence)	NM_012651.2
Accession Version	NM_012651.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2787bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	band 3 anion transport protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from L02943.1 and BC085748.1. On or before Jun 25, 2006 this sequence version replaced XM_001081509.1, NM_012651.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01906349, SAMN01906350 [ECO:0000348] ##Evidence-Data-END##

ATGGGGGACA TGCAGGACCA CGAGAAAGTG CTGGAGATCC CAGACCGTGA CAGTGAAGAG 
GAACTGGAAC ATGTAATAGA ACAGATAGCA TACAGAGACC TAGACATCCC TGTGACAGAA 
ATGCAGGAGT CAGAAGCTCT TCCCACAGAG CAAACAGCCA CAGACTACAT CCCCACCAGT 
ACCTCCACAT CGCACCCAAG CTCCAGTCAG GTCTATGTAG AGCTGCAGGA ACTGATGATG 
GACCAGAGGA ACCAGGAACT ACAGTGGGTG GAGGCGGCAC ACTGGATAGG GCTGGAGGAA 
AACCTTCGAG AGGATGGTGT GTGGGGTCGT CCACATCTCT CTTACCTCAC CTTCTGGAGC 
CTTCTAGAAC TGCAGAAGGT CTTCTCAAAA GGCACCTTCC TTCTGGATCT GGCAGAGACA 
TCCCTGGCTG GGGTGGCCAA TAAACTTCTA GACAGTTTCA TCTATGAGGA TCAAATTCGG 
CCTCAAGACC GAGATGAGCT GCTCCGGGCT CTGCTACTCA AACGCAGCCA CGCTGAGGAC 
CTAAAGGATC TGGAGGGAGT GAAGCCTGCC GTCCTGACCC GCTCTGGGGC CCCTTCTGAA 
CCTCTTCTTC CTCACCAGCC ATCGCTGGAG ACCAAGCTGT ACTGTGCACA GGCAGAGGGG 
GGCTCAGAAG AACCCTCGCC ATCTGGGATT CTGAAGATCC CCCCCAATTC AGAAACCACA 
TTGGTGCTAG TGGGCCGGGC TAGTTTCCTG GTGAAGCCTG TGCTGGGCTT CGTGAGACTG 
AAGGAAGCTG TGCCGCTGGA GGACCTGGTG TTGCCGGAGC CTGTGAGCTT CCTTCTAGTT 
CTTCTCGGAC CTGAGGCTCC GCACATCGAC TACACCCAGC TGGGCAGGGC TGCAGCAACT 
CTCATGACAG AAAGAGTGTT CCGCGTTACC GCCTCCCTGG CGCAGAGCCG AGGGGAGCTG 
CTGAGCTCCC TGGATAGCTT TCTGGACTGT AGCCTGGTGC TGCCGCCCAC AGAGGCCCCT 
TCAGAGAAAG CTCTGCTCAA CCTGGTGCCC GTGCAGAAGG AGTTGCTTAG GAAGCGGTAC 
TTGCCCAGAC CTGCCAAGCC AGACCCCAAC TTGTACGAGG CATTAGCAGA CGGGGGAAAG 
GAGGGCCCCG GTGACGAAGA CGACCCTCTA AGGCGCACCG GCCGGATCTT TGGAGGCCTG 
ATCCGTGATA TCCGGCGCCG GTATCCTTAC TACCTGAGTG ACATCACCGA TGCGCTCAGT 
CCCCAGGTGC TGGCTGCTGT CATCTTCATC TACTTTGCTG CCTTGTCACC TGCGGTCACC 
TTCGGCGGTC TCCTGGGAGA AAAGACCCGG AACCTGATGG GGGTGTCAGA GCTGCTCATC 
TCCACAGCAG TGCAAGGAAT TCTCTTTGCT CTCCTGGGGG CACAGCCCCT GCTTGTGCTC 
GGCTTCTCAG GACCCCTGCT GGTGTTTGAA GAAGCCTTCT ACTCGTTCTG TGAAAGCAAT 
AACCTGGAGT ACATCGTGGG CCGCGCGTGG ATCGGCTTCT GGCTTATCCT GCTGGTGGTG 
TTGGTGGTGG CCTTTGAAGG CAGCTTCCTG GTCCAATACA TCTCCCGCTA CACTCAGGAG 
ATCTTCTCCT TCCTCATCTC CCTCATCTTC ATCTATGAGA CTTTCTCTAA GCTGATCAAG 
ATTTTCCAGG ACTACCCGCT ACAAGAGAGC TATGCCCCTG TTGTGATGAA GCCCAAACCT 
CAGGGCCCCG TGCCCAACAC AGCCCTCCTC TCCCTTGTGC TTATGGTTGG TACCTTCCTA 
CTTGCCATGA TGCTACGAAA GTTCAAGAAC AGCACCTACT TCCCCGGCAA GCTACGCAGA 
GTCATTGGGG ACTTTGGGGT CCCCATCTCC ATCCTGATAA TGGTCCTGGT GGATACCTTC 
ATCAAGAACA CCTACACGCA GAAACTCTCG GTGCCTGATG GCCTTAAAGT GTCCAACTCC 
TCCGCCCGGG GCTGGGTCAT CCATCCCCTG GGTCTGTATA ACCATTTCCC CAAGTGGATG 
ATGTTTGCTT CTGTTCTACC CGCTCTGCTT GTCTTCATCC TTATATTCCT TGAGTCTCAG 
ATCACCACGC TGATTGTCAG TAAACCTGAG CGGAAGATGA TCAAGGGCTC CGGCTTCCAC 
CTGGACTTGC TGCTGGTTGT TGGCATGGGC GGGGTGGCCG CCCTCTTTGG GATGCCTTGG 
CTCAGCGCCA CCACTGTGCG TTCTGTTACC CATGCCAACG CCCTCACAGT CATGGGGAAG 
GCCAGTGGTC CAGGGGCTGC AGCCCAGATC CAAGAGGTCA AGGAACAGCG GATCAGTGGG 
CTCCTGGTCT CTGTGCTCGT GGGACTGTCC ATTCTCATGG AACCCATCCT GTCCCGCATC 
CCCCTGGCCG TACTGTTTGG CATCTTCCTG TACATGGGGA TCACATCCCT CAGTGGCATC 
CAGCTCTTTG ACCGCATCTT GCTCCTGTTC AAGCCACCCA AGTACCACCC AGATGTGCCC 
TTTGTCAAGA GGGTGAAGAC CTGGCGTATG CACCTCTTCA CGGGCATCCA GATCATCTGC 
CTGGCTGTGC TGTGGGTGGT GAAGTCCACG CCAGCCTCGC TGGCCCTGCC CTTTGTCCTC 
ATCCTCACCG TGCCCCTGCG TCGTCTCCTC CTGCCGCTCA TCTTCAGAGA GCTAGAACTC 
CAGTGTCTGG ATGGTGATGA TGCCAAAGTG ACCTTTGACG AGGCGGAAGG GCTGGATGAG 
TATGACGAAG TGCCCATGCC TGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036783.2
CDS	210..2996
Translation	MGDMQDHEKVLEIPDRDSEEELEHVIEQIAYRDLDIPVTEMQESEALPTEQTATDYIPTSTSTSHPSSSQVYVELQELMMDQRNQELQWVEAAHWIGLEENLREDGVWGRPHLSYLTFWSLLELQKVFSKGTFLLDLAETSLAGVANKLLDSFIYEDQIRPQDRDELLRALLLKRSHAEDLKDLEGVKPAVLTRSGAPSEPLLPHQPSLETKLYCAQAEGGSEEPSPSGILKIPPNSETTLVLVGRASFLVKPVLGFVRLKEAVPLEDLVLPEPVSFLLVLLGPEAPHIDYTQLGRAAATLMTERVFRVTASLAQSRGELLSSLDSFLDCSLVLPPTEAPSEKALLNLVPVQKELLRKRYLPRPAKPDPNLYEALADGGKEGPGDEDDPLRRTGRIFGGLIRDIRRRYPYYLSDITDALSPQVLAAVIFIYFAALSPAVTFGGLLGEKTRNLMGVSELLISTAVQGILFALLGAQPLLVLGFSGPLLVFEEAFYSFCESNNLEYIVGRAWIGFWLILLVVLVVAFEGSFLVQYISRYTQEIFSFLISLIFIYETFSKLIKIFQDYPLQESYAPVVMKPKPQGPVPNTALLSLVLMVGTFLLAMMLRKFKNSTYFPGKLRRVIGDFGVPISILIMVLVDTFIKNTYTQKLSVPDGLKVSNSSARGWVIHPLGLYNHFPKWMMFASVLPALLVFILIFLESQITTLIVSKPERKMIKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASGPGAAAQIQEVKEQRISGLLVSVLVGLSILMEPILSRIPLAVLFGIFLYMGITSLSGIQLFDRILLLFKPPKYHPDVPFVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRLLLPLIFRELELQCLDGDDAKVTFDEAEGLDEYDEVPMPV

Target ORF information:

RefSeq Version	NM_012651.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 4 member 1 (Diego blood group) (Slc4a1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012651.2

ORF Insert Sequence:

ATGGGGGACA TGCAGGACCA CGAGAAAGTG CTGGAGATCC CAGACCGTGA CAGTGAAGAG 
GAACTGGAAC ATGTAATAGA ACAGATAGCA TACAGAGACC TAGACATCCC TGTGACAGAA 
ATGCAGGAGT CAGAAGCTCT TCCCACAGAG CAAACAGCCA CAGACTACAT CCCCACCAGT 
ACCTCCACAT CGCACCCAAG CTCCAGTCAG GTCTATGTAG AGCTGCAGGA ACTGATGATG 
GACCAGAGGA ACCAGGAACT ACAGTGGGTG GAGGCGGCAC ACTGGATAGG GCTGGAGGAA 
AACCTTCGAG AGGATGGTGT GTGGGGTCGT CCACATCTCT CTTACCTCAC CTTCTGGAGC 
CTTCTAGAAC TGCAGAAGGT CTTCTCAAAA GGCACCTTCC TTCTGGATCT GGCAGAGACA 
TCCCTGGCTG GGGTGGCCAA TAAACTTCTA GACAGTTTCA TCTATGAGGA TCAAATTCGG 
CCTCAAGACC GAGATGAGCT GCTCCGGGCT CTGCTACTCA AACGCAGCCA CGCTGAGGAC 
CTAAAGGATC TGGAGGGAGT GAAGCCTGCC GTCCTGACCC GCTCTGGGGC CCCTTCTGAA 
CCTCTTCTTC CTCACCAGCC ATCGCTGGAG ACCAAGCTGT ACTGTGCACA GGCAGAGGGG 
GGCTCAGAAG AACCCTCGCC ATCTGGGATT CTGAAGATCC CCCCCAATTC AGAAACCACA 
TTGGTGCTAG TGGGCCGGGC TAGTTTCCTG GTGAAGCCTG TGCTGGGCTT CGTGAGACTG 
AAGGAAGCTG TGCCGCTGGA GGACCTGGTG TTGCCGGAGC CTGTGAGCTT CCTTCTAGTT 
CTTCTCGGAC CTGAGGCTCC GCACATCGAC TACACCCAGC TGGGCAGGGC TGCAGCAACT 
CTCATGACAG AAAGAGTGTT CCGCGTTACC GCCTCCCTGG CGCAGAGCCG AGGGGAGCTG 
CTGAGCTCCC TGGATAGCTT TCTGGACTGT AGCCTGGTGC TGCCGCCCAC AGAGGCCCCT 
TCAGAGAAAG CTCTGCTCAA CCTGGTGCCC GTGCAGAAGG AGTTGCTTAG GAAGCGGTAC 
TTGCCCAGAC CTGCCAAGCC AGACCCCAAC TTGTACGAGG CATTAGCAGA CGGGGGAAAG 
GAGGGCCCCG GTGACGAAGA CGACCCTCTA AGGCGCACCG GCCGGATCTT TGGAGGCCTG 
ATCCGTGATA TCCGGCGCCG GTATCCTTAC TACCTGAGTG ACATCACCGA TGCGCTCAGT 
CCCCAGGTGC TGGCTGCTGT CATCTTCATC TACTTTGCTG CCTTGTCACC TGCGGTCACC 
TTCGGCGGTC TCCTGGGAGA AAAGACCCGG AACCTGATGG GGGTGTCAGA GCTGCTCATC 
TCCACAGCAG TGCAAGGAAT TCTCTTTGCT CTCCTGGGGG CACAGCCCCT GCTTGTGCTC 
GGCTTCTCAG GACCCCTGCT GGTGTTTGAA GAAGCCTTCT ACTCGTTCTG TGAAAGCAAT 
AACCTGGAGT ACATCGTGGG CCGCGCGTGG ATCGGCTTCT GGCTTATCCT GCTGGTGGTG 
TTGGTGGTGG CCTTTGAAGG CAGCTTCCTG GTCCAATACA TCTCCCGCTA CACTCAGGAG 
ATCTTCTCCT TCCTCATCTC CCTCATCTTC ATCTATGAGA CTTTCTCTAA GCTGATCAAG 
ATTTTCCAGG ACTACCCGCT ACAAGAGAGC TATGCCCCTG TTGTGATGAA GCCCAAACCT 
CAGGGCCCCG TGCCCAACAC AGCCCTCCTC TCCCTTGTGC TTATGGTTGG TACCTTCCTA 
CTTGCCATGA TGCTACGAAA GTTCAAGAAC AGCACCTACT TCCCCGGCAA GCTACGCAGA 
GTCATTGGGG ACTTTGGGGT CCCCATCTCC ATCCTGATAA TGGTCCTGGT GGATACCTTC 
ATCAAGAACA CCTACACGCA GAAACTCTCG GTGCCTGATG GCCTTAAAGT GTCCAACTCC 
TCCGCCCGGG GCTGGGTCAT CCATCCCCTG GGTCTGTATA ACCATTTCCC CAAGTGGATG 
ATGTTTGCTT CTGTTCTACC CGCTCTGCTT GTCTTCATCC TTATATTCCT TGAGTCTCAG 
ATCACCACGC TGATTGTCAG TAAACCTGAG CGGAAGATGA TCAAGGGCTC CGGCTTCCAC 
CTGGACTTGC TGCTGGTTGT TGGCATGGGC GGGGTGGCCG CCCTCTTTGG GATGCCTTGG 
CTCAGCGCCA CCACTGTGCG TTCTGTTACC CATGCCAACG CCCTCACAGT CATGGGGAAG 
GCCAGTGGTC CAGGGGCTGC AGCCCAGATC CAAGAGGTCA AGGAACAGCG GATCAGTGGG 
CTCCTGGTCT CTGTGCTCGT GGGACTGTCC ATTCTCATGG AACCCATCCT GTCCCGCATC 
CCCCTGGCCG TACTGTTTGG CATCTTCCTG TACATGGGGA TCACATCCCT CAGTGGCATC 
CAGCTCTTTG ACCGCATCTT GCTCCTGTTC AAGCCACCCA AGTACCACCC AGATGTGCCC 
TTTGTCAAGA GGGTGAAGAC CTGGCGTATG CACCTCTTCA CGGGCATCCA GATCATCTGC 
CTGGCTGTGC TGTGGGTGGT GAAGTCCACG CCAGCCTCGC TGGCCCTGCC CTTTGTCCTC 
ATCCTCACCG TGCCCCTGCG TCGTCTCCTC CTGCCGCTCA TCTTCAGAGA GCTAGAACTC 
CAGTGTCTGG ATGGTGATGA TGCCAAAGTG ACCTTTGACG AGGCGGAAGG GCTGGATGAG 
TATGACGAAG TGCCCATGCC TGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc4a1 ( XM_008767946.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008766168.1 Rattus norvegicus solute carrier family 4 (anion exchanger), member 1 (Slc4a1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa33645
Clone ID Related Accession (Same CDS sequence)	XM_008767946.2
Accession Version	XM_008767946.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2784bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	band 3 anion transport protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767946.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGACA TGCAGGACCA CGAGAAAGTG CTGGAGATCC CAGACCGTGA CAGTGAAGAG 
GAACTGGAAC ATGTAATAGA ACAGATAGCA TACAGAGACC TAGACATCCC TGTGACAGAA 
ATGCAGGAGT CAGAAGCTCT TCCCACAGAG CAAACAGCCA CAGACTACAT CCCCACCAGT 
ACCTCCACAT CGCACCCAAG CTCCAGTCAG GTCTATGTAG AGCTGCAGGA ACTGATGATG 
GACCAGAGGA ACCAGGAACT ACAGTGGGTG GAGGCGGCAC ACTGGATAGG GCTGGAGGAA 
AACCTTCGAG AGGATGGTGT GTGGGGTCGT CCACATCTCT CTTACCTCAC CTTCTGGAGC 
CTTCTAGAAC TGCAGAAGGT CTTCTCAAAA GGCACCTTCC TTCTGGATCT GGCAGAGACA 
TCCCTGGCTG GGGTGGCCAA TAAACTTCTA GACAGTTTCA TCTATGAGGA TCAAATTCGG 
CCTCAAGACC GAGATGAGCT GCTCCGGGCT CTGCTACTCA AACGCAGCCA CGCTGAGGAC 
CTAAAGGATC TGGAGGGAGT GAAGCCTGCC GTCCTGACCC GCTCTGGGGC CCCTTCTGAA 
CCTCTTCTTC CTCACCAGCC ATCGCTGGAG ACCAAGCTGT ACTGTGCACA GGCAGAGGGG 
GGCTCAGAAG AACCCTCGCC ATCTGGGATT CTGAAGATCC CCCCCAATTC AGAAACCACA 
TTGGTGCTAG TGGGCCGGGC TAGTTTCCTG GTGAAGCCTG TGCTGGGCTT CGTGAGACTG 
AAGGAAGCTG TGCCGCTGGA GGACCTGGTG TTGCCGGAGC CTGTGAGCTT CCTTCTAGTT 
CTTCTCGGAC CTGAGGCTCC GCACATCGAC TACACCCAGC TGGGCAGGGC TGCAGCAACT 
CTCATGACAG AAAGAGTGTT CCGCGTTACC GCCTCCCTGG CGCAGAGCCG AGGGGAGCTG 
CTGAGCTCCC TGGATAGCTT TCTGGACTGT AGCCTGGTGC TGCCGCCCAC AGAGGCCCCT 
TCAGAGAAAG CTCTGCTCAA CCTGGTGCCC GTGCAGAAGG AGTTGCTTAG GAAGCGGTAC 
TTGCCCAGAC CTGCCAAGCC AGACCCCAAC TTGTACGAGG CATTAGACGG GGGAAAGGAG 
GGCCCCGGTG ACGAAGACGA CCCTCTAAGG CGCACCGGCC GGATCTTTGG AGGCCTGATC 
CGTGATATCC GGCGCCGGTA TCCTTACTAC CTGAGTGACA TCACCGATGC GCTCAGTCCC 
CAGGTGCTGG CTGCTGTCAT CTTCATCTAC TTTGCTGCCT TGTCACCTGC GGTCACCTTC 
GGCGGTCTCC TGGGAGAAAA GACCCGGAAC CTGATGGGGG TGTCAGAGCT GCTCATCTCC 
ACAGCAGTGC AAGGAATTCT CTTTGCTCTC CTGGGGGCAC AGCCCCTGCT TGTGCTCGGC 
TTCTCAGGAC CCCTGCTGGT GTTTGAAGAA GCCTTCTACT CGTTCTGTGA AAGCAATAAC 
CTGGAGTACA TCGTGGGCCG CGCGTGGATC GGCTTCTGGC TTATCCTGCT GGTGGTGTTG 
GTGGTGGCCT TTGAAGGCAG CTTCCTGGTC CAATACATCT CCCGCTACAC TCAGGAGATC 
TTCTCCTTCC TCATCTCCCT CATCTTCATC TATGAGACTT TCTCTAAGCT GATCAAGATT 
TTCCAGGACT ACCCGCTACA AGAGAGCTAT GCCCCTGTTG TGATGAAGCC CAAACCTCAG 
GGCCCCGTGC CCAACACAGC CCTCCTCTCC CTTGTGCTTA TGGTTGGTAC CTTCCTACTT 
GCCATGATGC TACGAAAGTT CAAGAACAGC ACCTACTTCC CCGGCAAGCT ACGCAGAGTC 
ATTGGGGACT TTGGGGTCCC CATCTCCATC CTGATAATGG TCCTGGTGGA TACCTTCATC 
AAGAACACCT ACACGCAGAA ACTCTCGGTG CCTGATGGCC TTAAAGTGTC CAACTCCTCC 
GCCCGGGGCT GGGTCATCCA TCCCCTGGGT CTGTATAACC ATTTCCCCAA GTGGATGATG 
TTTGCTTCTG TTCTACCCGC TCTGCTTGTC TTCATCCTTA TATTCCTTGA GTCTCAGATC 
ACCACGCTGA TTGTCAGTAA ACCTGAGCGG AAGATGATCA AGGGCTCCGG CTTCCACCTG 
GACTTGCTGC TGGTTGTTGG CATGGGCGGG GTGGCCGCCC TCTTTGGGAT GCCTTGGCTC 
AGCGCCACCA CTGTGCGTTC TGTTACCCAT GCCAACGCCC TCACAGTCAT GGGGAAGGCC 
AGTGGTCCAG GGGCTGCAGC CCAGATCCAA GAGGTCAAGG AACAGCGGAT CAGTGGGCTC 
CTGGTCTCTG TGCTCGTGGG ACTGTCCATT CTCATGGAAC CCATCCTGTC CCGCATCCCC 
CTGGCCGTAC TGTTTGGCAT CTTCCTGTAC ATGGGGATCA CATCCCTCAG TGGCATCCAG 
CTCTTTGACC GCATCTTGCT CCTGTTCAAG CCACCCAAGT ACCACCCAGA TGTGCCCTTT 
GTCAAGAGGG TGAAGACCTG GCGTATGCAC CTCTTCACGG GCATCCAGAT CATCTGCCTG 
GCTGTGCTGT GGGTGGTGAA GTCCACGCCA GCCTCGCTGG CCCTGCCCTT TGTCCTCATC 
CTCACCGTGC CCCTGCGTCG TCTCCTCCTG CCGCTCATCT TCAGAGAGCT AGAACTCCAG 
TGTCTGGATG GTGATGATGC CAAAGTGACC TTTGACGAGG CGGAAGGGCT GGATGAGTAT 
GACGAAGTGC CCATGCCTGT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008766168.1
CDS	215..2998
Translation	MGDMQDHEKVLEIPDRDSEEELEHVIEQIAYRDLDIPVTEMQESEALPTEQTATDYIPTSTSTSHPSSSQVYVELQELMMDQRNQELQWVEAAHWIGLEENLREDGVWGRPHLSYLTFWSLLELQKVFSKGTFLLDLAETSLAGVANKLLDSFIYEDQIRPQDRDELLRALLLKRSHAEDLKDLEGVKPAVLTRSGAPSEPLLPHQPSLETKLYCAQAEGGSEEPSPSGILKIPPNSETTLVLVGRASFLVKPVLGFVRLKEAVPLEDLVLPEPVSFLLVLLGPEAPHIDYTQLGRAAATLMTERVFRVTASLAQSRGELLSSLDSFLDCSLVLPPTEAPSEKALLNLVPVQKELLRKRYLPRPAKPDPNLYEALDGGKEGPGDEDDPLRRTGRIFGGLIRDIRRRYPYYLSDITDALSPQVLAAVIFIYFAALSPAVTFGGLLGEKTRNLMGVSELLISTAVQGILFALLGAQPLLVLGFSGPLLVFEEAFYSFCESNNLEYIVGRAWIGFWLILLVVLVVAFEGSFLVQYISRYTQEIFSFLISLIFIYETFSKLIKIFQDYPLQESYAPVVMKPKPQGPVPNTALLSLVLMVGTFLLAMMLRKFKNSTYFPGKLRRVIGDFGVPISILIMVLVDTFIKNTYTQKLSVPDGLKVSNSSARGWVIHPLGLYNHFPKWMMFASVLPALLVFILIFLESQITTLIVSKPERKMIKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASGPGAAAQIQEVKEQRISGLLVSVLVGLSILMEPILSRIPLAVLFGIFLYMGITSLSGIQLFDRILLLFKPPKYHPDVPFVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRLLLPLIFRELELQCLDGDDAKVTFDEAEGLDEYDEVPMPV

Target ORF information:

RefSeq Version	XM_008767946.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 4 (anion exchanger), member 1 (Slc4a1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008767946.2

ORF Insert Sequence:

ATGGGGGACA TGCAGGACCA CGAGAAAGTG CTGGAGATCC CAGACCGTGA CAGTGAAGAG 
GAACTGGAAC ATGTAATAGA ACAGATAGCA TACAGAGACC TAGACATCCC TGTGACAGAA 
ATGCAGGAGT CAGAAGCTCT TCCCACAGAG CAAACAGCCA CAGACTACAT CCCCACCAGT 
ACCTCCACAT CGCACCCAAG CTCCAGTCAG GTCTATGTAG AGCTGCAGGA ACTGATGATG 
GACCAGAGGA ACCAGGAACT ACAGTGGGTG GAGGCGGCAC ACTGGATAGG GCTGGAGGAA 
AACCTTCGAG AGGATGGTGT GTGGGGTCGT CCACATCTCT CTTACCTCAC CTTCTGGAGC 
CTTCTAGAAC TGCAGAAGGT CTTCTCAAAA GGCACCTTCC TTCTGGATCT GGCAGAGACA 
TCCCTGGCTG GGGTGGCCAA TAAACTTCTA GACAGTTTCA TCTATGAGGA TCAAATTCGG 
CCTCAAGACC GAGATGAGCT GCTCCGGGCT CTGCTACTCA AACGCAGCCA CGCTGAGGAC 
CTAAAGGATC TGGAGGGAGT GAAGCCTGCC GTCCTGACCC GCTCTGGGGC CCCTTCTGAA 
CCTCTTCTTC CTCACCAGCC ATCGCTGGAG ACCAAGCTGT ACTGTGCACA GGCAGAGGGG 
GGCTCAGAAG AACCCTCGCC ATCTGGGATT CTGAAGATCC CCCCCAATTC AGAAACCACA 
TTGGTGCTAG TGGGCCGGGC TAGTTTCCTG GTGAAGCCTG TGCTGGGCTT CGTGAGACTG 
AAGGAAGCTG TGCCGCTGGA GGACCTGGTG TTGCCGGAGC CTGTGAGCTT CCTTCTAGTT 
CTTCTCGGAC CTGAGGCTCC GCACATCGAC TACACCCAGC TGGGCAGGGC TGCAGCAACT 
CTCATGACAG AAAGAGTGTT CCGCGTTACC GCCTCCCTGG CGCAGAGCCG AGGGGAGCTG 
CTGAGCTCCC TGGATAGCTT TCTGGACTGT AGCCTGGTGC TGCCGCCCAC AGAGGCCCCT 
TCAGAGAAAG CTCTGCTCAA CCTGGTGCCC GTGCAGAAGG AGTTGCTTAG GAAGCGGTAC 
TTGCCCAGAC CTGCCAAGCC AGACCCCAAC TTGTACGAGG CATTAGACGG GGGAAAGGAG 
GGCCCCGGTG ACGAAGACGA CCCTCTAAGG CGCACCGGCC GGATCTTTGG AGGCCTGATC 
CGTGATATCC GGCGCCGGTA TCCTTACTAC CTGAGTGACA TCACCGATGC GCTCAGTCCC 
CAGGTGCTGG CTGCTGTCAT CTTCATCTAC TTTGCTGCCT TGTCACCTGC GGTCACCTTC 
GGCGGTCTCC TGGGAGAAAA GACCCGGAAC CTGATGGGGG TGTCAGAGCT GCTCATCTCC 
ACAGCAGTGC AAGGAATTCT CTTTGCTCTC CTGGGGGCAC AGCCCCTGCT TGTGCTCGGC 
TTCTCAGGAC CCCTGCTGGT GTTTGAAGAA GCCTTCTACT CGTTCTGTGA AAGCAATAAC 
CTGGAGTACA TCGTGGGCCG CGCGTGGATC GGCTTCTGGC TTATCCTGCT GGTGGTGTTG 
GTGGTGGCCT TTGAAGGCAG CTTCCTGGTC CAATACATCT CCCGCTACAC TCAGGAGATC 
TTCTCCTTCC TCATCTCCCT CATCTTCATC TATGAGACTT TCTCTAAGCT GATCAAGATT 
TTCCAGGACT ACCCGCTACA AGAGAGCTAT GCCCCTGTTG TGATGAAGCC CAAACCTCAG 
GGCCCCGTGC CCAACACAGC CCTCCTCTCC CTTGTGCTTA TGGTTGGTAC CTTCCTACTT 
GCCATGATGC TACGAAAGTT CAAGAACAGC ACCTACTTCC CCGGCAAGCT ACGCAGAGTC 
ATTGGGGACT TTGGGGTCCC CATCTCCATC CTGATAATGG TCCTGGTGGA TACCTTCATC 
AAGAACACCT ACACGCAGAA ACTCTCGGTG CCTGATGGCC TTAAAGTGTC CAACTCCTCC 
GCCCGGGGCT GGGTCATCCA TCCCCTGGGT CTGTATAACC ATTTCCCCAA GTGGATGATG 
TTTGCTTCTG TTCTACCCGC TCTGCTTGTC TTCATCCTTA TATTCCTTGA GTCTCAGATC 
ACCACGCTGA TTGTCAGTAA ACCTGAGCGG AAGATGATCA AGGGCTCCGG CTTCCACCTG 
GACTTGCTGC TGGTTGTTGG CATGGGCGGG GTGGCCGCCC TCTTTGGGAT GCCTTGGCTC 
AGCGCCACCA CTGTGCGTTC TGTTACCCAT GCCAACGCCC TCACAGTCAT GGGGAAGGCC 
AGTGGTCCAG GGGCTGCAGC CCAGATCCAA GAGGTCAAGG AACAGCGGAT CAGTGGGCTC 
CTGGTCTCTG TGCTCGTGGG ACTGTCCATT CTCATGGAAC CCATCCTGTC CCGCATCCCC 
CTGGCCGTAC TGTTTGGCAT CTTCCTGTAC ATGGGGATCA CATCCCTCAG TGGCATCCAG 
CTCTTTGACC GCATCTTGCT CCTGTTCAAG CCACCCAAGT ACCACCCAGA TGTGCCCTTT 
GTCAAGAGGG TGAAGACCTG GCGTATGCAC CTCTTCACGG GCATCCAGAT CATCTGCCTG 
GCTGTGCTGT GGGTGGTGAA GTCCACGCCA GCCTCGCTGG CCCTGCCCTT TGTCCTCATC 
CTCACCGTGC CCCTGCGTCG TCTCCTCCTG CCGCTCATCT TCAGAGAGCT AGAACTCCAG 
TGTCTGGATG GTGATGATGC CAAAGTGACC TTTGACGAGG CGGAAGGGCT GGATGAGTAT 
GACGAAGTGC CCATGCCTGT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cluster of erythrocyte band 3: a potential molecular target of exhaustive exercise-induced dysfunction of erythrocyte deformability.
Canadian journal of physiology and pharmacology91(12)1127-34(2013 Dec)
Xiong Y,Li Y,Xiong Y,Zhao Y,Tang F,Wang X

A substrate access tunnel in the cytosolic domain is not an essential feature of the solute carrier 4 (SLC4) family of bicarbonate transporters.
The Journal of biological chemistry288(47)33848-60(2013 Nov)
Shnitsar V,Li J,Li X,Calmettes C,Basu A,Casey JR,Moraes TF,Reithmeier RA

Activity and distribution of intracellular carbonic anhydrase II and their effects on the transport activity of anion exchanger AE1/SLC4A1.
The Journal of physiology591(20)4963-82(2013 Oct)
Al-Samir S,Papadopoulos S,Scheibe RJ,Mei?ner JD,Cartron JP,Sly WS,Alper SL,Gros G,Endeward V

Natural antiband 3 antibodies in patients with sickle cell disease.
Comptes rendus biologies336(3)173-6(2013 Mar)
Villaescusa R,Arce AA,Lalanne-Mistrih ML,Lamarre Y,Hierso R,Hern?ndez C,Hardy-Dessources MD,

Tropical distal renal tubular acidosis: clinical and epidemiological studies in 78 patients.
QJM : monthly journal of the Association of Physicians105(9)861-77(2012 Sep)
Khositseth S,Bruce LJ,Walsh SB,Bawazir WM,Ogle GD,Unwin RJ,Thong MK,Sinha R,Choo KE,Chartapisak W,Kingwatanakul P,Sumboonnanonda A,Vasuvattakul S,Yenchitsomanus P,Wrong O

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Slc4a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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