Antibody Affinity Maturation
10 - 50 fold Affinity Improvement
Antibody Affinity Maturation Service
お問合せ
Antibody Affinity Maturation Service (Cat. No.: SC1574)
| Service Includes | Deliverable | Timeline |
| Antibody sequencing and sequence analysis | - Antibody sequence, report of sequence analysis
| 24 weeks |
| Library design and construction | - Library plasmid and glycerol stock, Report of library development
|
| Phage display and FASEBA screening | - Top five Fab candidates; Report of screening
|
| Antibody production and characterization | - Final report and purified antibody
|
| The following is GenScript's standard affinity maturation service procedure:  Please find out more for FASEBA technology here  |
| GenScript offers our customers a one-stop solution for all outsourcing needs, providing comprehensive upstream and downstream services of monoclonal antibody sequencing service. |
Key Features: - Proprietary FASEBA technology for guaranteed protein stability
- Affinity maturated to at least low nM or improved 10 fold
- Affinity assessed with BIAcore T200
- Expression level evaluated
Affinity is a key parameter of an antibody and often defines its functions and efficacy. Antibodies generated with hybridoma technology usually have a relatively high affinity but this affinity may still not suffice the need of a therapeutic antibody. GenScript's Antibody Affinity Maturation Service (Cat. No.: SC1574) can increase the affinity to an ideal level. |
|
